Urodynamic Changes and Initial Results of the AdVance Male Sling

Davies, Timothy O.; Bepple, Jennifer L.; McCammon, Kurt

doi:10.1016/j.urology.2008.12.082

Cited by 90 publications

(63 citation statements)

References 19 publications

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“…The mechanism of the male sling is not well-understood, but likely relies on increased bladder outlet resistance during the storage phase or valsalva. 11,12 Unlike the AUS, success of the male sling may depend on the ability to generate detrusor contraction of adequate strength and the duration to empty the bladder, without valsalva.…”

Section: Introductionmentioning

confidence: 99%

Detrusor underactivity is prevalent after radical prostatectomy: a urodynamic study including risk factors

Chung

Dillon

Kurta

et al. 2012

CUAJ

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Introduction: The objective was to determine the prevalence of, and factors that predict, detrusor underactivity (DU) in patients presenting with incontinence or lower urinary tract symptoms (LUTS) following radical prostatectomy (RP). We also determined the prevalence of bladder outlet obstruction (BOO) and detrusor overactivity (DO) in this population. Methods: Patients who underwent urodynamics post-RP were identified. Detrusor underactivity was defined as a maximum flow rate (Qmax) of ≤15 mL/s and detrusor pressure (Pdet) Qmax <20 cmH20 or maximum Pdet <20 cmH20 during attempted voiding. Abdominal voiding (AV) was defined as sustained increase in abdominal pressure during voiding. Bladder outlet obstruction and DO were identified using the Abrams-Griffiths nomogram and the International Continence Society criteria. Univariate logistic regression was used to determine factors predicting DU. The following factors were analyzed: age, year of RP, procedure type (minimally-invasive surgery [MIS] or open), postoperative radiation, nerve-sparing, clinical stage, biopsy Gleason grade and interval between RP and evaluation. Results: Between 2005 and 2008, 264 patients underwent urodynamics post-RP. Detrusor underactivity was observed in 108 patients (41%; 95% CI 35%, 47%), of whom 48% demonstrated AV. Overall, BOO and DO were present in 17% (95% CI 12%, 22%) and 27% (95% CI 22%, 33%), respectively. On univariate analysis, only MIS RP was predictive of DU (univariate odds ratio 2.05 for MIS vs. open; p = 0.009). Conclusions: Detrusor underactivity and AV are common in patients presenting for evaluation of incontinence or LUTS following RP. The etiology of DU in this setting is likely related to the surgical approach. Because DU may affect the success of male incontinence treatment with the male sling or artificial urinary sphincter, it is useful to document its presence prior to treatment. More studies are needed to elucidate the influence of DU on treatment success for male urinary incontinence following RP.

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Section: Introductionmentioning

confidence: 99%

Detrusor underactivity is prevalent after radical prostatectomy: a urodynamic study including risk factors

Chung

Dillon

Kurta

et al. 2012

CUAJ

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“…The AdVance TM transobturator tape increases urethral closure pressure and membranous urethral length without significantly affecting maximum urinary flow rate, detrusor voiding pressure, or post void residual urine. 34,35 However, these results need to be confirmed independently. Obviously, large long-term follow-up RCTs comparing tapes to AUS are necessary to evaluate clinical application of this concept.…”

Section: Slings-tapesmentioning

confidence: 98%

Post‐prostatectomy stress urinary incontinence: What treatment for which patient?

Gajewski

Drake

Oelke

2010

Neurourology and Urodynamics

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Several factors may influence the analysis of endothelial cells (ECs) by flow cytometry: separation of mononuclear cell, washing and centrifugation steps, panel of monoclonal antibodies, and the lack of standardization of gating technique. Therefore, the reliable quantification of ECs remains a technical challenge. The purpose of this study is to define a new flow cytometric protocol to characterize and quantitate ECs. In previous investigations, increased numbers of circulating ECs have been found in sickle cell disease. The patients with sickle cell disease might provide useful material for the study. We performed flow cytometry on whole blood from 20 normal controls and 31 patients with sickle cell disease (20 patients with steady‐state disease and 11 patients with vaso‐occlusive crises) using a lyse/no‐wash procedure, specific and nonspecific antibody combinations (CD146, CD144, CD34, and CD117), and broad gating. This protocol produced much higher values for the number of circulating ECs (a mean of 2,396.55 ± 658.37 ECs/mL in controls vs 6,709.60 ± 1,772.32 ECs/mL in the steady‐state group, or 18,213.50 ± 8,451 in the vaso‐occlusive crises group, P < 0.001 for both), and also showed variable EC size and granularity, which may reflect activated, or early release ECs. This novel protocol performed comparably in terms of reproducibility, reliability, and dilution linearity with a previously described protocol. This approach has significant advantages for the characterization and quantitation ECs compatible with the pathophysiology. Using the specific antibodies, CD146 and CD144, together may give more informative EC data than the general approach used. Am. J. Hematol., 2007. © 2007 Wiley‐Liss, Inc.

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“…bare Obstruktion wird durch das Ausleiten der Schlinge durch die Fossa obturatoria verhindert [10]. Bei einer prospektiven Studie von 137 Patienten werden Erfolgsraten von 75% (51% Heilung, 24% Verbesserung) berichtet [3].…”

Section: Studieunclassified

Behandlung der männlichen Harninkontinenz

Leicht

Thüroff

2012

Urologe

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Different kinds of sling systems for the therapy of male urinary incontinence have been developed during the last decade. All systems work by compressing the male urethra. There are adjustable and non-adjustable systems. Implantation is mostly a minimally invasive procedure. On the other hand the well-established AMS 800 hydraulic artificial sphincter has been available since 1972. Recently, another hydraulic artificial sphincter (FlowSecure) has become available providing a boost of occlusive pressure during stress. The aim of this review is to compare effectiveness and indications of the different techniques compared to the artificial sphincter.

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Urodynamic Changes and Initial Results of the AdVance Male Sling

Cited by 90 publications

References 19 publications

Detrusor underactivity is prevalent after radical prostatectomy: a urodynamic study including risk factors

Detrusor underactivity is prevalent after radical prostatectomy: a urodynamic study including risk factors

Post‐prostatectomy stress urinary incontinence: What treatment for which patient?

Behandlung der männlichen Harninkontinenz

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