Urine Catalytic Iron and Neutrophil Gelatinase Associated Lipocalin as Companion Early Markers of Acute Kidney Injury After Cardiac Surgery: A Prospective Pilot Study
Abstract:Background: Open heart surgery with cardiopulmonary bypass is recognized as a common cause of acute kidney injury (AKI). The conventional biomarker creatinine is not sensitive enough to detect AKI until a significant decline in renal filtration has occurred. Urine neutrophil gelatinase-associated lipocalin (NGAL), part of an acute response to the release of tissue iron from cells, is an early biomarker and a predictor of AKI in a variety of clinical settings. We sought to evaluate the relationship between urin… Show more
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