Urinary Tract Infections Following Transurethral Prostatectomy: With Special Reference to the Use of Antimicrobials

Genster, H; Madsen, Paul O.

doi:10.1016/s0022-5347(17)61692-6

Cited by 70 publications

(8 citation statements)

References 18 publications

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“…The incidence of both fever and bacteriuria demon strated in this study corresponds to previous findings [1,[6][7][8][9][10][11], Bacteriuria may give rise to urinary tract infection and fever, disappear spontaneously, or be quite asymptom atic [7,12], When systematic antibiotic prophylaxis is not used it may be important that patients observed without antibiotic treatment show a negative urine culture. This was the case in the present study in 90% of the patients with postoperative fever and in 95% without, indicating that the clinical evaluation had been a sufficient basis for deciding against antimicrobial therapy.…”

Section: Discussionsupporting

confidence: 89%

Value of Clinical Decision on Antibiotic Treatment of Fever Episodes following Transurethral Resection of the Prostate

Hartzen¹,

Skaarup²,

Bremmelgaard³

1986

Urol Int

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The value of clinical decision on antibiotic treatment of fever episodes following transurethral resection of the prostate was assessed in 134 patients. Besides bacteriuria, need of blood transfusions and various catheter problems were associated with a significant number of fever episodes. The majority of patients with fever not given antibiotic therapy had negative urine cultures (90%), whereas 41 % of the patients with fever treated with antibiotics showed negative urine cultures indicating an overtreatment of these patients. Out of the total number of patients, only 10% with subsequent negative urine cultures received antibiotics, a figure which should be compared to the inevitable rate of overtreatment when general antibiotic prophylaxis is preferred.

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Section: Discussionsupporting

confidence: 89%

Value of Clinical Decision on Antibiotic Treatment of Fever Episodes following Transurethral Resection of the Prostate

Hartzen¹,

Skaarup²,

Bremmelgaard³

1986

Urol Int

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“…8,12 On the other hand, in patients who have a positive urine culture at the time of the operation, the occurrence of fever, bacteremic episodes and postoperative urinary tract infection can be minimized by prior treatment, as shown by other authors. [12][13][14][15] This seems to be the rationale for the usage of antibiotic.…”

Section: Discussionmentioning

confidence: 99%

A randomized and prospective study on the value of antibiotic prophylaxis administration in transurethral resection of the prostate

et al. 2004

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CONTEXT: Antibiotic prophylaxis in transurethral resection of the prostate is a regular practice in urology. However, its prophylactic effect can be questioned when the antiseptic surgical technique is used. Nonetheless, urine culture-oriented antibiotic therapy is the gold standard for avoiding improper medication usage and bacterial resistance. OBJECTIVE: To study the efficacy of antibiotic usage in patients with negative urine cultures, who were submitted to transurethral resection of the prostate. TYPE OF STUDY: Prospective open labeled study. SETTING: Tertiary care referral hospital PARTICIPANTS: 124 consecutive patients, who were randomly divided into two groups to receive antibiotic prophylaxis or not. MAIN MEASUREMENTS: Cultures from meatus, urine, irrigation and antiseptic fluid, and prostate tissue chips, were compared and analyzed for bacterial sensitivity to the antibiotic used, according to the surgeon's personal criteria. McLennan's test was used for statistical analysis. RESULTS: No statistically significant difference regarding clinical evolution was found between the groups that received or antibiotics or not. Statistical significance was found regarding the occurrence of positive urine cultures during the postoperative period for those not receiving antibiotics, but not in relation to fever, prostate chip culture or bacteremic episodes. Sixty-eight subjects (57.1%) presented positive prostatic tissue culture. There was no specific correlation between the recovered bacteria from the meatus, prostatic tissue chip and urine and the spectrum of the administered antibiotic. Six cases showed the same bacteria in the urine and prostatic tissue chip. Only fifteen cases (25%) in the antibiotic group showed the desired sensitivity directed to the collected bacteria. CONCLUSIONS: Antibiotic prophylaxis for patients whose urine is sterile is debatable in patients who are candidates for transurethral resection of the prostate. Most of the time, the antibiotic agent used is not specific for any of the bacteria recovered from the various sources analyzed.

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“…In 1960, volume 88 of the Journal of Urology also included eight TUR‐orientated papers; seven of these strictly used the full terminology and only one resorted to TUR (mentioned four times) [19]. In 1970, volume 104 of the Journal of Urology contained five such papers; one resorted to a TUR abbreviation only in figures, two only spelled out transurethral resection and two made extensive use of TUR and TURP (for a total of 34 uses) [20–24].…”

Section: Urological Acronyms and Other Initialismsmentioning

confidence: 99%

Acronyms, abbreviations and initialisms

Grange¹,

Bloom

2000

BJU International

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Urinary Tract Infections Following Transurethral Prostatectomy: With Special Reference to the Use of Antimicrobials

Cited by 70 publications

References 18 publications

Value of Clinical Decision on Antibiotic Treatment of Fever Episodes following Transurethral Resection of the Prostate

Value of Clinical Decision on Antibiotic Treatment of Fever Episodes following Transurethral Resection of the Prostate

A randomized and prospective study on the value of antibiotic prophylaxis administration in transurethral resection of the prostate

Acronyms, abbreviations and initialisms

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