Urinary oxalate estimation

Olthuis, F.M.F.G.; Markslag, A. M. G.; Elhorst, J.T.Klein; Dagneaux, P. G. L. C. Krugers

doi:10.1016/0009-8981(77)90507-1

Cited by 33 publications

(3 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Until 1988, urine oxalate was measured using the method of Olthuis et al 22 (normal reference range, 0.23 to 0.68 mmol/24 h). The immobilized oxalate oxidase method has been used since to determine oxalate concentrations in both urine and plasma, with a normal reference range of 0.11 to 0.46 mmol/24 h in urine and 0.4 to 3.0 mol/L in plasma.…”

Section: Analytic Methodsmentioning

confidence: 99%

Combined liver-kidney and kidney-alone transplantation in primary hyperoxaluria

Monico

Milliner

2001

Liver Transplantation

View full text Add to dashboard Cite

Combined liver-kidney and kidney-only transplantation outcomes in primary hyperoxaluria (PH) are described. Strategies for the selection of type and timing of transplantation and pretransplantation and posttransplantation management are reviewed. Records were reviewed for 16 patients with PH who received 9 liver-kidney and 10 kidney-only transplants. Plasma oxalate values declined from 61 ؎ 42 mol/L pretransplantation to 9 ؎ 6 mol/L 1 month after transplantation in liver-kidney transplant recipients and 92 ؎ 19 to 9 ؎ 5 mol/L in kidney-only transplant recipients. In most liver-kidney transplant recipients, hyperoxaluria persisted for 6 to 18 months after transplantation. Follow-up was 3.5 ؎ 4.1 years in liver-kidney and 4.5 ؎ 6.3 years in kidney-alone transplant recipients. Patient survival rates were 78% for liver-kidney and 89% for kidney-only transplant recipients. No hepatic allografts were lost. Three of 9 liverkidney and 6 of 10 kidney-alone transplants lost renal allograft function. In those with functioning kidneys, renal clearance was 45.1 ؎ 19.5 mL/min/1.73 m 2 in liverkidney transplant recipients and 49.5 ؎ 26.1 mL/min/ 1.73 m 2 in kidney-only transplant recipients at last follow-up. Kaplan-Meier 1-, 2-, 3-, and 5-year renal allograft survival rates for patients undergoing transplantation after 1984 were 78%, 78%, 52%, and 52% in liver-kidney transplant recipients and 86%, 71%, 54%, and 36% in kidney-only transplant recipients. Simultaneous grafting of liver and kidney after the development of renal insufficiency is recommended for the majority of patients with PH type I (PH-I). Kidney-alone transplantation is recommended for those with pyridoxine-responsive type I disease because pharmacological therapy allows favorable management of oxalate production in this situation. Kidney-alone transplantation also is recommended for PH type II (PH-II). This disease is less severe than PH-I, and it is currently unknown whether liver transplantation will correct the metabolic defect responsible for PH-II. (Liver Transpl 2001;7:954-963.)

show abstract

Section: Analytic Methodsmentioning

confidence: 99%

Combined liver-kidney and kidney-alone transplantation in primary hyperoxaluria

Monico

Milliner

2001

Liver Transplantation

View full text Add to dashboard Cite

show abstract

“…Urinary oxalate was measured by a combined ionic chromatographic and spectrophotometric technique (26) (reference range 100-520 pmoY24 h). Urinary citrate was determined by a citrate lyase method (38).…”

Section: Urine Analysismentioning

confidence: 99%

Intestinal Absorption of Oxalate and Calcium in Patients with Jejunoileal Bypass

Lindsjö

Danielson

Fellström

et al. 1989

Scandinavian Journal of Urology and Nephrology

View full text Add to dashboard Cite

Jejunoileal bypass (JIB) has been widely performed for treatment of excessive obesity. Formation of calcium oxalate stones is a common side effect. Since, under physiological conditions, the intestinal absorption of calcium and that of oxalate are interrelated, intestinal oxalate and calcium absorption were measured in the present study by isotope techniques in 19 JIB patients and 20 healthy controls. The JIB patients showed pronounced hyperoxaluria and markedly increased absorption of oxalate, with a urinary excretion of 14C-oxalate of 29 +/- 19% (controls 6.2 +/- 3.7%; p less than 0.001). There was a strong correlation between the intestinal absorption and urinary excretion of oxalate in the JIB patients (r = 0.72; p less than 0.001). Furthermore, their oxalate kinetics was altered, with continued urinary excretion of 14C-oxalate for up to 48 hours. The JIB patients also had reduced calcium absorption (36 +/- 9.1% vs. 47 +/- 9.0%; p less than 0.001) and patients with malabsorption of calcium and low urinary calcium had the highest intestinal absorption and urinary excretion of oxalate. It is concluded that hyperoxaluria in JIB patients is due to a significant extent to hyperabsorption of oxalate.

show abstract

“…A third method, ion-exchange chromatography, is probably the least used method of the three for preliminary separation of oxalate. Anion exchange resins, Lewatit MP 7080, Dowex AG 2-X8, Carbopack B, and DEAE-Sephadex, have been used successfully; however, inconsistent recovery of oxalate and time-consuming procedures preclude this method of oxalate separation for routine laboratory usage (Di Corcia et al, 1982;Johansson and Tabova, 1974;Olthuis et al, 1977;Sims et al, 1981). More recently, an octadecyl-silane bonded-phase packing (Sep-Pak C^g cartridge) has been used for initial clean-up of urine samples (Larsson et al, 1982).…”

Section: Urinementioning

confidence: 99%

Microbial degradation of oxalate in the gastrointestinal tracts of rodents and ruminants

Daniel

View full text Add to dashboard Cite

Urinary oxalate estimation

Cited by 33 publications

References 6 publications

Combined liver-kidney and kidney-alone transplantation in primary hyperoxaluria

Combined liver-kidney and kidney-alone transplantation in primary hyperoxaluria

Intestinal Absorption of Oxalate and Calcium in Patients with Jejunoileal Bypass

Microbial degradation of oxalate in the gastrointestinal tracts of rodents and ruminants

Contact Info

Product

Resources

About