Urinary organophosphate metabolites and oxidative stress in children living in agricultural and urban communities

Sapbamrer, Ratana; Hongsibsong, Surat; Khacha-ananda, Supakit

doi:10.1007/s11356-020-09037-z

Cited by 10 publications

(2 citation statements)

References 44 publications

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“…This study suggests that children may be exposed to OPs both inside and outside the home and that this exposure can cause oxidative stress in children. Oxidative stress contributes to the development of chronic diseases and is recommended to be measured as a biomarker among children exposed to POs as a preventive way to identify chronic diseases ( 90 ).…”

Section: Resultsmentioning

confidence: 99%

Frequency of urinary pesticides in children: a scoping review

Guzman-Torres,

Sandoval-Pinto,

Cremades

et al. 2023

Front. Public Health

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Pesticides are any mix of ingredients and substances used to eliminate or control unwanted vegetable or animal species recognized as plagues. Its use has been discussed in research due to the scarcity of strong scientific evidence about its health effects. International literature is still insufficient to establish a global recommendation through public policy. This study aims to explore international evidence of the presence of pesticides in urine samples from children and their effects on health through a scoping review based on the methodology described by Arksey and O‘Malley. The number of articles resulting from the keyword combination was 454, and a total of 93 manuscripts were included in the results and 22 were complementary. Keywords included in the search were: urinary, pesticide, children, and childhood. Children are exposed to pesticide residues through a fruit and vegetable intake environment and household insecticide use. Behavioral effects of neural damage, diabetes, obesity, and pulmonary function are health outcomes for children that are commonly studied. Gas and liquid chromatography-tandem mass spectrometry methods are used predominantly for metabolite-pesticide detection in urine samples. Dialkylphosphates (DAP) are common in organophosphate (OP) metabolite studies. First-morning spot samples are recommended to most accurately characterize OP dose in children. International evidence in PubMed supports that organic diets in children are successful interventions that decrease the urinary levels of pesticides. Several urinary pesticide studies were found throughout the world's population. However, there is a knowledge gap that is important to address (public policy), due to farming activities that are predominant in these territories.

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Section: Resultsmentioning

confidence: 99%

Frequency of urinary pesticides in children: a scoping review

Guzman-Torres,

Sandoval-Pinto,

Cremades

et al. 2023

Front. Public Health

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“…Firstly, the concentration of herbicides from occupational exposure may not be high sufficient to generate ROS, so the level of ROS may not be enough to disrupt lipid of cell membrane. Secondly, anioxidant defenses in the body can reduce ROS and maintain redox homeostasis resulting in unchange the level of 8-isoprostane 25,26 .…”

Section: Discussionmentioning

confidence: 99%

Decreased Antioxidant Capacity in Corn Farmers Occupationally Exposed to the Mixture of Herbicides

Unchisa Intayoung,

Kanyapak Kohsuwan,

Klintean Wunnapuk

et al. 2021

Indian Journal of Forensic Medicine & Toxicology

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Background: The application of herbicides has been a common practice in worldwide agriculture, mainly with the goal to increase efficacy of weed control. So, most farmers faced a greater risk of herbicide exposure to develop adverse health effects from oxidative stress-induced herbicides. The aim of this study is to determine the urinary total antioxidant capacity (TAC) and 8-isoprostane levels in farmers using the

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