Urinary minerals excretion among primary schoolchildren in Dubai—United Arab Emirates

Ghali, Rola Al; El-Mallah, Carla; Obeid, Omar; El-Saleh, Ola; Smail, Linda; Haroun, Dalia

doi:10.1371/journal.pone.0255195

Cited by 6 publications

(3 citation statements)

References 56 publications

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“…Notably, iodine deficiency problems in the UAE have diminished since 1994, with IDDs prevalence ranging from mild to normal across the country [ 5 ]. A study conducted in 2021 assessing urinary mineral excretion among primary school children in the emirate of Dubai revealed that only 10% of the Emirati population exhibited deficient iodine levels [ 6 ]. These findings are based on the median urinary iodine concentrations following the guidelines of the WHO [ 7 , 8 ].…”

Section: Discussionmentioning

confidence: 99%

Knowledge, Attitudes, and Practices of Iodized Salt Among Adults Aged 18 to 65 in the United Arab Emirates

Salma,

Musameh,

Motawea

et al. 2024

Cureus

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Background: Iodine plays a big role in growth and development and is used in the synthesis of thyroid hormones that regulate body organ functions. Its most important source is iodized salt. Iodine deficiency impairs cognitive development and precipitates many thyroid diseases. Aim: The purpose of our study is to measure the knowledge, attitudes, and practices towards iodized salt in adults aged 18-65 years in the United Arab Emirates. Methods: This is a cross-sectional study that included 406 participants. A self-administered questionnaire was distributed in public places across the Emirates. The survey included the socio-demographic characteristics of the participants with questions related to knowledge, attitudes, and practices towards iodized salt. A knowledge score out of 13 was calculated. Chi-square, Mann-Whitney U, and Independent T-tests were used for analysis on the Statistical Package for the Social Sciences (IBM SPSS Statistics for Windows, IBM Corp., Version 22.0, Armonk, NY), with a p-value less than 5% considered statistically significant. Results: Out of the 406 respondents, 60% (n=246) were between the ages of 18-34 years and 71% (n=287) were at university level. The mean knowledge score was higher in participants with higher educational levels compared to participants with lower education levels (4.30 vs 2.63, respectively) and in older ages (35-65 years) compared to younger ages (18-34 years) (4.20 vs 3.59, respectively). Almost half of the participants buy iodized salt (48%, n=196), a minority buy non-iodized salt (14%, n=55), and the rest do not know what type of salt they buy. Most of the participants who use iodized salt store it in a closed container and do not expose it to sunlight. Conclusion: Knowledge about iodized salt is relatively low. Less than half of the participants use it, while most of the participants who use iodized salt follow the right storage recommendations. Our study suggests the implementation of public campaigns to raise awareness about the importance of iodized salt and the benefits of using it.

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Section: Discussionmentioning

confidence: 99%

Knowledge, Attitudes, and Practices of Iodized Salt Among Adults Aged 18 to 65 in the United Arab Emirates

Salma,

Musameh,

Motawea

et al. 2024

Cureus

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“…When serum albumin was <4.0 g/dL, then the following formula was used: corrected calcium (mg/dL) = measured Ca (mg/dL) + 4 − measured albumin (g/dL) [31]. Urinary protein and phosphate levels were normalized to those of creatinine (Cr), and then expressed as g/gCr, as previously described [32].…”

Section: Physical and Laboratory Measurements And Other Clinical Info...mentioning

confidence: 99%

Short-Term Dapagliflozin Administration in Autosomal Dominant Polycystic Kidney Disease—A Retrospective Single-Arm Case Series Study

Morioka,

Nakatani,

Uedono

et al. 2023

JCM

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Treatment with sodium-glucose cotransporter-2 (SGLT2) inhibitors may have pleiotropic and beneficial effects in terms of ameliorating of risk factors for the progression of autosomal dominant polycystic kidney disease (ADPKD). However, there is insufficient evidence regarding the use of these drugs in patients with ADPKD, as they were excluded from several clinical trials conducted to explore kidney protection provided by SGLT2 inhibitors. This retrospective single-arm case series study was performed to investigate the effects of dapagliflozin, a selective SGLT2 inhibitor administered at 10 mg/day, on changes in height-adjusted kidney volume (htTKV) and estimated glomerular filtration rate (eGFR) in ADPKD patients. During a period of 102 ± 20 days (range 70–156 days), eGFR was decreased from 47.9 (39.7–56.9) to 40.8 (33.7–44.5) mL/min/1.73 m2 (p < 0.001), while htTKV was increased from 599 (423–707) to 617 (446–827) mL/m (p = 0.002) (n = 20). The annual increase in htTKV rate was significantly promoted, and urinary phosphate change was found to be correlated with the change in htTKV (rs = 0.575, p = 0.020). In the examined patients, eGFR was decreased and htTKV increased during short-term administration of dapagliflozin. To confirm the possibility of the effects of dapagliflozin on ADPKD, additional interventional studies are required.

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“…However, the upper limit of U Ca /U Cr is controversial for accurately determining hypercalciuria. [ 16 ] Spot U Pro /U Cr ratio >0.7 mg/mg is defined as proteinuria. [ 17 ]…”

Section: Aterials and M Ethodsmentioning

confidence: 99%

Kidney failure in children with Wilms tumor: A study based on urine analysis and ultrasound

et al. 2022

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Background: Renal insufficiency is one of the inevitable complications in patients with Wilms tumor (WT). The purpose of this study was to assess the renal function in children with WT at baseline and every 3 months to 2 years. Materials and Methods: In a descriptive-analytical study from 2018 to 2020, 48 children with WT were included in the study. Urine creatinine (U Cr ), serum calcium (S Cr ), blood pressure (BP), estimated glomerular filtration rate (eGFR), and urinary protein (U Pro ) were evaluated at baseline and every 3 months during the study. Spot U Ca /U Cr and spot U Pro /U Cr ratio were calculated. Kidney ultrasonography was used in all patients. Independent Sample t -test and Chi-square tests were utilized to compare age and sex, respectively. Results: The mean age of patients at follow-up was 7.3 years. There was no significant difference in mean U Cr , S Cr , eGFR, 24-h U Pro , U Ca /U Cr ratio, and spot U Pro /U Cr ratio at baseline and end of study ( P baseline > 0.05, P end of study > 0.05). Analysis of kidney size showed a statistical association with tumor stage ( P < 0.05). Comparison of the kidney size in patients showed that there is a statistically significant difference ( P < 0.0001) at baseline and end of the study. Conclusion: This study showed that as WT progressed, the size of the kidneys increases without any renal insufficiency. Therefore, it seems that urinalysis of patients with WT along with sonography is necessary to determine renal insufficiency and the use of ultrasound alone to determine kidney insufficiency is not recommended.

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Urinary minerals excretion among primary schoolchildren in Dubai—United Arab Emirates

Cited by 6 publications

References 56 publications

Knowledge, Attitudes, and Practices of Iodized Salt Among Adults Aged 18 to 65 in the United Arab Emirates

Knowledge, Attitudes, and Practices of Iodized Salt Among Adults Aged 18 to 65 in the United Arab Emirates

Short-Term Dapagliflozin Administration in Autosomal Dominant Polycystic Kidney Disease—A Retrospective Single-Arm Case Series Study

Kidney failure in children with Wilms tumor: A study based on urine analysis and ultrasound

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