Urinary Levels of 1-Hydroxypyrene, 1-, 2-, 3-, and 4-Hydroxyphenanthrene in Females Living in an Industrial Area of Germany

Gündel, J.; Mannschreck, C.; Büttner, U. Ewers K.

doi:10.1007/s002449900148

Cited by 17 publications

(27 citation statements)

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“…Other factors such as diet could be important (Falco et al, 2003;Scherer et al, 2000). Pregnant women in this study had higher levels of creatinine adjusted OH-PAHs compared to levels observed in charcoal workers in Brazil (Kato et al, 2004), but are comparable to those observed in non-smoking women in a city in the industrial Ruhr Valley in Germany (Gündel et al, 1996). Concentration of creatinine adjusted 1-PYR was higher in female cooks who worked in a mill in China and cooked with wood, coal briquette or LPG (~2 times higher) (Chen et al, 2007), and in a rural Burundi population exposed to indoor biomass smoke mainly from the combustion of wood (~3.5 times higher) (Viau et al, 2000) compared to the pregnant women in this study.…”

Section: Discussionsupporting

confidence: 68%

Biomonitoring of polycyclic aromatic hydrocarbon exposure in pregnant women in Trujillo, Peru — Comparison of different fuel types used for cooking

Adetona

Sjödin

et al. 2013

Environment International

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Women and children in developing countries are often exposed to high levels of air pollution including polycyclic aromatic hydrocarbons (PAHs), which may negatively impact their health, due to household combustion of biomass fuel for cooking and heating. We compared creatinine adjusted hydroxy-PAH (OH-PAH) concentrations in pregnant women in Trujillo, Peru who cook with wood to levels measured in those who cook with kerosene, liquefied petroleum gas or a combination of fuels. Seventy-nine women were recruited for the study between May and July 2004 in the first trimester of their pregnancy. Urine samples were collected from the subjects in the first, second and third trimesters for OH-PAH analyses. The concentrations of the OH-PAHs were compared across the type of fuel used for cooking and pregnancy trimesters. The relationships between OH-PAHs levels in the first trimester and concurrently measured personal exposures to PM 2.5 , carbon monoxide and nitrogen dioxide together with their indoor and outdoor air concentrations were also investigated. Women cooking with wood or kerosene had the highest creatinine adjusted OH-PAH concentrations compared with those using gas, coal briquette or a combination of fuels. Concentrations of creatinine adjusted 2-hydroxy-fluorene, 3-hydroxyfluorene, 1-hydroxy-fluorene, 2-hydroxy-phenanthrene and 4-hydroxy-phenanthrene were significantly higher (p<0.05) in women who used wood or kerosene alone compared with women who used liquefied petroleum gas (LPG), coal briquette or a combination of fuels. An increase in the concentrations of creatinine adjusted 9-hydroxy-fluorene, 1-hydroxy-phenanthrene, 2- Conflict of interest statementThe authors declare no conflict of interest. HHS Public Access Author Manuscript Author ManuscriptAuthor ManuscriptAuthor Manuscript hydroxy-phenanthrene, 4-hydroxy-phenanthrene and 1-hydroxy-pyrene in the third trimesters was also observed. Weak positive correlation (Spearman correlation coefficient, ρ<0.4; p<0.05) was observed between all first trimester creatinine adjusted OH-PAHs and indoor (kitchen and living room), and personal 48-h TWA PM 2.5 . Women who cooked exclusively with wood or kerosene had higher creatinine adjusted OH-PAH levels in their urine samples compared to women who cooked with LPG or coal briquette.

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Section: Discussionsupporting

confidence: 68%

Biomonitoring of polycyclic aromatic hydrocarbon exposure in pregnant women in Trujillo, Peru — Comparison of different fuel types used for cooking

Adetona

Sjödin

et al. 2013

Environment International

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“…Our analytic method measured 14 hydroxylated metabolites in urine. The most common PAH metabolite used for biomonitoring exposure is 1-hydroxypyrene, having been studied in a variety of environmental settings (Bouchard et al 2001;Gilbert and Viau 1997;Gundel et al 1996;Scherer et al 2000;Viau et al 2000), aluminum refining (Levin et al 1995;Ny et al 1993;Ovrebo et al 1995b;Van Schooten et al 1995), and coke production (Mielynska et al 1997;Ovrebo et al 1995a;Pan et al 1998;van Delft et al 2001;VanRooij et al 1993;Wu et al 1998).…”

Section: Discussionmentioning

confidence: 99%

Biomonitoring of chemical exposure among New York City firefighters responding to the World Trade Center fire and collapse.

Edelman

Osterloh

Pirkle

et al. 2003

Environ Health Perspect

117

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The collapse of the World Trade Center (WTC) on 11 September 2001 exposed New York City firefighters to smoke and dust of unprecedented magnitude and duration. The chemicals and the concentrations produced from any fire are difficult to predict, but estimates of internal dose exposures can be assessed by the biological monitoring of blood and urine. We analyzed blood and urine specimens obtained from 321 firefighters responding to the WTC fires and collapse for 110 potentially fire-related chemicals. Controls consisted of 47 firefighters not present at the WTC. Sampling occurred 3 weeks after 11 September, while fires were still burning. When reference or background ranges were available, most chemical concentrations were found to be generally low and not outside these ranges. Compared with controls, the exposed firefighters showed significant differences in adjusted geometric means for six of the chemicals and significantly greater detection rates for an additional three. Arrival time was a significant predictor variable for four chemicals. Special Operations Command firefighters (n = 95), compared with other responding WTC firefighters (n = 226), had differences in concentrations or detection rate for 14 of the chemicals. Values for the Special Operations Command firefighters were also significantly different from the control group values for these same chemicals and for two additional chemicals. Generally, the chemical concentrations in the other firefighter group were not different from those of controls. Biomonitoring was used to characterize firefighter exposure at the WTC disaster. Although some of the chemicals analyzed showed statistically significant differences, these differences were generally small.

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“…Such loadings may occur through discharge of industrial effluents and through accidental release of raw and refined products. However, PAHs released into the environment may originate from many sources, including gasoline and diesel fuel combustion (68,71) and tobacco smoke (35), for example. PAHs are detected in air (63,68), soil and sediment (47,64,65,79,99,118), surface water, groundwater, and road runoff (11,46,72,83); are dispersed from the atmosphere to vegetation (101); and contaminate foods (25,67,89).…”

Section: Pahs In the Environmentmentioning

confidence: 99%

Biodegradation of High-Molecular-Weight Polycyclic Aromatic Hydrocarbons by Bacteria

2000

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Urinary Levels of 1-Hydroxypyrene, 1-, 2-, 3-, and 4-Hydroxyphenanthrene in Females Living in an Industrial Area of Germany

Cited by 17 publications

References 0 publications

Biomonitoring of polycyclic aromatic hydrocarbon exposure in pregnant women in Trujillo, Peru — Comparison of different fuel types used for cooking

Biomonitoring of polycyclic aromatic hydrocarbon exposure in pregnant women in Trujillo, Peru — Comparison of different fuel types used for cooking

Biomonitoring of chemical exposure among New York City firefighters responding to the World Trade Center fire and collapse.

Biodegradation of High-Molecular-Weight Polycyclic Aromatic Hydrocarbons by Bacteria

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