Aims: To evaluate the relationship between obesity and urinary incontinence (UI) and to determine the effect of weight reduction on the severity of incontinence. (Bristol, UK): "What are the relationships between obesity and UI, and the effects of successful bariatric surgery?"Results: Obesity is an increasing problem worldwide and is associated with many adverse effects on health and quality of life. From both translational and clinical studies, there is a strong relationship between obesity and the occurrence of UI.Both mechanical and metabolic factors seem to play an important role including systemic inflammation and oxidative stress due to the release of cytokines in visceral adipose tissue. The success rate of anti-incontinence surgery does not seem to be greatly affected by body mass index (BMI), although reliable data and longterm follow-up are currently lacking. Both weight reduction programs and bariatric surgery can result in amelioration of UI. Various studies have shown that weight loss (particularly that associated with bariatric surgery) can reduce incontinence, and the degree of weight loss is positively correlated with improvement in symptoms. Conclusions: Obesity is strongly associated with an increased prevalence of both stress and urgency UI. The treatment outcome does not seem to be highly dependent on BMI. Weight reduction is positively correlated with improvement of incontinence symptoms and therefore should be advocated in the management.
K E Y W O R D Sbariatric surgery, obesity, overweight, urinary incontinence 1 | INTRODUCTION Obesity has become a major global health challenge and the worldwide prevalence of obesity has nearly tripled between 1975 and 2016. According to the latest report of the World Health Organization more than 1.9 billion adults (39% of men and 40% of women) were overweight (body mass index [BMI], ≥25 kg/m 2 ) in 2016 and over