Urinary dysfunction in multiple sclerosis

Autonomic dysfunction in multiple sclerosis

“…This was corroborated by urodynamic studies, which found detrusor hyperreflexia to be the main abnormality present, followed by detrusor sphincter dyssinergia and the least number of MS patients showing detrusor hyporeflexia [34]. The most common urinary symptom reported from the same group of patients was urgency followed by frequency, urge incontinence, stress incontinence and dysuria [34].…”

Autonomic dysfunction in multiple sclerosis

“…Urodynamic tests are commonly performed to assess bladder dysfunction in patients reporting symptoms. The usual urodynamic findings are detrusor hyperreflexia, hyporeflexia and, most commonly, detrusor dyssynergia (Nakipoglu et al, 2009). Symptoms associated with detrusor instability are characterized by increased urinary frequency, urgency and nocturia, whereas intermittency, weak stream and straining at the beginning of urination are indicative of incomplete emptying (Kojima et al, 1997).…”

Intermittent catheterization with hydrophilic catheters as a treatment of chronic neurogenic urinary retention

“…1 Neurogenic detrusor overactivity occurs in 27% of patients with multiple sclerosis 2 and 72% of patients with a suprasacral spinal cord injury. 3 This neurogenic detrusor overactivity may occur in combination with sphincteric hypertonicity, known as detrusor-external sphincter dyssynergia (occurring in about 25% of patients with multiple sclerosis 2 and 81% of patients with a suprasacral spinal cord injury.…”

“…3 This neurogenic detrusor overactivity may occur in combination with sphincteric hypertonicity, known as detrusor-external sphincter dyssynergia (occurring in about 25% of patients with multiple sclerosis 2 and 81% of patients with a suprasacral spinal cord injury. 3 Damage to the reflex voiding center in the sacral area of the spinal cord results in areflexic bladder; reflexes and bladder activity are diminished, resulting in over-distension of the bladder.…”

“…1 Detrusor hyporeflexia is reported in 6% of patients with multiple sclerosis 2 and 43% of patients with sacral spinal cord injury. 3 There are few data for spina bifida, but in one survey of 109 patients using a variety of bladder management techniques, only 47% were dry.…”