Uridine-Loaded Polycaprolactone Nanofiber Mats as a Novel Wound Dressing
Hilmiye Sule Mergen,
Sebnem Duzyer Gebizli,
Erkan Ermis
et al.
Abstract:In the current study, a novel wound dressing material for an effective wound healing was developed by loading Uridine (URD), an endogenous compound known for its regenerative properties, into polycaprolactone (PCL) nanofibers. Initially, PCL nanofibers without URD were fabricated from different PCL solutions (7, 8, 10 and 11% w/w) by electrospinning and optimum PCL concentration (10% w/w) for URD loading was determined. After loading URD at different concentrations (0.1, 0.5 and 1% w/w) into 10% PCL solution, … Show more
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