Uretral foreign body; Evaluation of an interesting case guided by the literature

Abstract

The present study aims to examine the protective effects of barbaloin on renal injured by cecal ligation and puncture (CLP) model. Methods: In our study, animals were divided into four groups. Study groups were designed as follows: sham, CLP, DMSO+CLP and 20 mg/kg barbaloin+CLP. Oxidative stress and cytokines were evaluated in renal tissues obtained at the end of the experiment. Results: The findings showed that the TOS, OSI, MPO, MDA, TNF-α and IL-1β increased and TAS and SOD decreased in the CLP group, but in the treatment group, molecule concentrations changed significantly. Conclusion: Our results have demonstrated that of barbaloin is effective against kidney injury caused by CLP-induced polymicrobial sepsis model.