Urethral involvement in granulomatosis with polyangiitis: a case-based review

Ahmed, Hamdy; Elfishawi, Mohanad; Hagiga, Ahmed; Ahmed, Ibrahim S.; Chen, Ya Li

doi:10.1007/s00296-019-04331-7

Cited by 4 publications

(10 citation statements)

References 27 publications

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“…Genitourinary involvement in GPA is exceedingly rare, with <1% of GPA cases involving the genitourinary system [ 1 ]. In a review by Ahmed et al, urethral involvement in GPA is more common in men than women [ 2 ]. The most common urogenital manifestation of GPA reported in men is prostatitis (in 12–37% of cases of GPA with urogenital involvement), but orchitis, urethritis, genital ulcers, penile involvement and renal masses from GPA have been reported in men as well [ 1 , 2 ].…”

Section: Discussionmentioning

confidence: 99%

“…In a review by Ahmed et al, urethral involvement in GPA is more common in men than women [ 2 ]. The most common urogenital manifestation of GPA reported in men is prostatitis (in 12–37% of cases of GPA with urogenital involvement), but orchitis, urethritis, genital ulcers, penile involvement and renal masses from GPA have been reported in men as well [ 1 , 2 ]. In women, four cases of urethral involvement of systemic GPA have been reported [ 2 ].…”

Section: Discussionmentioning

confidence: 99%

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Initial presentation of granulomatosis with polyangiitis as urethral mass mimicking urethral cancer: A case report

Mohanty¹,

San²,

Bell

et al. 2023

Case Reports in Women's Health

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Initial presentation of granulomatosis with polyangiitis as urethral mass mimicking urethral cancer: A case report

Mohanty¹,

San²,

Bell

et al. 2023

Case Reports in Women's Health

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“…Rare cases with female genital organ involvement, such as the uterus, mainly cervix, ovaries, or fallopian tubes, are reported (2). Isolated bladder and urethra involvement are rarely reported (1,3).…”

Section: Discussionmentioning

confidence: 99%

“…Our literature review revealed that few cases of lower urinary tract vasculitis have been described. Bladder vasculitis are extremely rare (1,3). Vasculitis affecting the female genital tract has been reported more often.…”

Section: Discussionmentioning

confidence: 99%

“…Based on studies that investigated the impact of vasculite on female reproductive organs and urinary tract, it can be argued that in most cases, vasculitis has been diagnosed in the uterus, which ovary has been recognized after resection surgery (3,4,6,7). In urinary tract, where resection of organ (bladder, urethra) is very mutilating or devastating, the diagnosis is based on a biopsy that can be further supported by imaging techniques such as tomography and resonance.…”

Section: Discussionmentioning

confidence: 99%

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A Rare Case of Vasculitis ANCA of Bladder and Urethra Providing to Vesicovaginal Fistula and Early Recurrence of Illness

Gawlik-Jakubczak

2021

Nephro-Urol Mon

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Introduction: Vasculitis of the bladder and urethra is a rare disease. Its presentation, as a pelvis tumor, indicates the cancerous nature of the lesion. An incorrect diagnosis can result in the removal of the bladder. Case Presentation: We described a 56-year-old woman (born in 1964) with a vesicovaginal fistula, which arose from vasculitis ANCA. Establishing the correct diagnosis was a long and complicated process. During diagnosis, a urogenital fistula was created due to the deepening of inflammatory necrotic lesions. Remission was achieved by pharmacological treatment. As a result, fistula surgical treatment became possible. An unexpected relapse of vasculitis was diagnosed based on the bladder emptying symptoms. Repeating the treatment resulted in a complete response. Eventually, we obtained a cure of regional vasculitis while maintaining the bladder and urethra, which translated into an increased quality of life for the patient. Conclusions: Correct diagnosis before surgery is of crucial importance. Combined pharmacology and surgery prevents removal of the bladder. Careful observation of symptoms allowed for the early detection of recurrent vasculitis.

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Granulomatosis With Polyangiitis of Spinal Dura Presenting With “Bottle Brush Sign” on 18F-FDG PET/CT

Zhang,

Wu,

Shi

et al. 2024

Clin Nucl Med

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A 72-year-old man with fever and weakness in both lower limbs underwent thoracolumbar MRI and 18F-FDG PET/CT. The PET/CT scan revealed diffused FDG uptake along the spinal dura mater from T7 to S2 level like a “bottle brush.” Pathologic examination after biopsy of spinal canal lesions manifested granulomatous inflammation. The blood test showed cytoplasmic antineutrophil cytoplasmic antibody (ANCA) and myeloperoxidase-ANCAs were positive, whereas the perinuclear ANCA was negative. Eventually, he was diagnosed with granulomatosis with polyangiitis.

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Urethral involvement in granulomatosis with polyangiitis: a case-based review

Cited by 4 publications

References 27 publications

Initial presentation of granulomatosis with polyangiitis as urethral mass mimicking urethral cancer: A case report

Initial presentation of granulomatosis with polyangiitis as urethral mass mimicking urethral cancer: A case report

A Rare Case of Vasculitis ANCA of Bladder and Urethra Providing to Vesicovaginal Fistula and Early Recurrence of Illness

Granulomatosis With Polyangiitis of Spinal Dura Presenting With “Bottle Brush Sign” on 18F-FDG PET/CT

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