Ureteral Fibroepithelial Polyps in Four Dogs

Abstract

Four dogs with ureteral fibroepithelial polyps, ranging from 9-12 years of age, are presented in this report. The patients presented with urinary incontinence, urinary tract infection, and/or polydypsia and pollakiuria. All dogs were intact at the time of diagnosis or for the majority of their lives and three were male. Various diagnostic procedures were performed including ultrasonography, contrast radiography, and nuclear scintigraphy. Not all procedures were performed in all patients. Findings included ureteral dilation proximal to the level of an intraluminal mass and ipsilateral hydronephrosis. Unilateral ureteronephrectomy was performed in three dogs with masses in the proximal ureter; ureteral resection and anastamosis was performed in the remaining patient with a mass located in the distal ureter. The same pathologist (RAP) reviewed all four lesions. The lesions appeared polypoid and were attached to the ureteral wall by a thin stalk. Histopathologically, they contained a superficial layer of well-differentiated transitional epithelial cells overlying a prominent fibrovascular stroma with a mild (three dogs) or marked (one dog) degree of lymphoplasmacytic inflammation. This disease may represent a benign neoplasm or a chronic inflammatory reaction and has a good prognosis with surgical removal. Its histopathological characteristics, higher incidence in males, and location more commonly within the upper third of the ureter is remarkably similar to the disease in humans.

Primary ureteral giant cell sarcoma in a Pomeranian

“…This is the first report of a primary ureteral giant cell tumor in a dog. Similar to previous cases of ureteral tumors, this dog was presented with clinical signs associated with ureteral obstruction causing hydroureter and hydronephrosis . There were a few cytologic criteria of malignancy, and histologic evaluation illustrated that the mesenchymal neoplasm was covered with transitional epithelium and had minimal association with local tissue, suggesting that the tumor was slow‐growing.…”

Urinary Tract

“…29,30,92,[94][95][96] Obstruction due to ureteral inflammation, blood clots, fibroepithelial polyps, calculi, extrinsic masses, ureteral fibrosis, or strictures is less common [97][98][99][100][101][102][103] (see C to I,[16][17][18][19][20][21][22][23][24][25]. In most cases, a bladder, urethral, or prostatic tumor involving the trigone is responsible for ureteral obstruction.…”

Ureteral Fibroepithelial Polyp in an Owl Monkey (Aotus nancymae)

“…Histopathologically, they contained a superficial layer of well-differentiated transitional epithelial cells overlying a prominent fibrovascular stroma with varying degrees of lymphoplasmacytic inflammation. 8 The histopathologic characteristics, sex predisposition, and location, more commonly within the upper third of the ureter, were similar to the most common disease pattern in humans. 8 In this specific case, the fibroepithelial polyp location, histopathologic characteristics, sex, and age of the owl monkey were also consistent with the most common clinical and pathologic presentation observed in humans.…”

“…8 The histopathologic characteristics, sex predisposition, and location, more commonly within the upper third of the ureter, were similar to the most common disease pattern in humans. 8 In this specific case, the fibroepithelial polyp location, histopathologic characteristics, sex, and age of the owl monkey were also consistent with the most common clinical and pathologic presentation observed in humans. The polypoid shape resembled that described for the dog.…”

“…In animals, ureteral fibroepithelial polyps have only been reported in dogs. 8 In this report, we describe a ureteral fibroepithelial polyp in an owl monkey.…”