Urease Inhibitory Activity in Placental Extract

Abstract

In this study, we found human placental extract (HPEx) has urease inhibitory activity. In addition, HPEx was biochemically or chemically treated and fractionated to obtain the enzyme digested (EHY) and acid hydrolyzed (AHY) fractions. The inhibitory activity of EHY was lower than that of HPEx, whereas the inhibitory activity of AHY increased 2.4 fold. Furthermore, Lineweaver-Burk plot analysis indicated that type of inhibition of AHY showed mixed.