Urbanization and geographic expansion of zoonotic arboviral diseases: mechanisms and potential strategies for prevention

Weaver, Scott C.

doi:10.1016/j.tim.2013.03.003

Cited by 188 publications

(181 citation statements)

References 15 publications

(20 reference statements)

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“…In order to reduce disease burden, reductions in urban mosquito-human transmission seem to be the only option [83]. Since 80 % of infected individuals are asymptomatic, mosquito bites avoidance such as personal protection helps to disrupt human-to-mosquito-to-human transmission cycles [76].…”

Section: Reduction Of Urban Mosquito-human Transmissionmentioning

confidence: 99%

Zika Virus Infection: Current Concerns and Perspectives

Maharajan

Ranjan

Chu

et al. 2016

Clinic Rev Allerg Immunol

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Section: Reduction Of Urban Mosquito-human Transmissionmentioning

confidence: 99%

Zika Virus Infection: Current Concerns and Perspectives

Maharajan

Ranjan

Chu

et al. 2016

Clinic Rev Allerg Immunol

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“…Yellow fever (YF) virus (YFV) is a major public health problem in Africa and South America, with a history of causing epidemics worldwide including the U.S. (Ishikawa et al, 2014; Paessler and Walker, 2013; Weaver, 2013). The World Health Organization estimates 200 000 cases of YF and 30 000 deaths worldwide annually.…”

Section: Introductionmentioning

confidence: 99%

“…Phylogenetic and epidemiological analysis supports a model of YFV emergence that is dependent upon both the presence of competent mosquito vectors and nonhuman primate reservoir hosts (Grard et al, 2010; Quaresma et al, 2013). The dynamic ecological and climatic changes associated with international travel, trade, and urbanization increase the potential of YF spread to previously non-endemic regions of the world (Weaver, 2013). …”

Section: Introductionmentioning

confidence: 99%

Plasmid DNA initiates replication of yellow fever vaccine in vitro and elicits virus-specific immune response in mice

et al. 2014

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Yellow fever (YF) causes an acute hemorrhagic fever disease in tropical Africa and Latin America. To develop a novel experimental YF vaccine, we applied iDNA infectious clone technology. The iDNA represents plasmid that encodes the full-length RNA genome of 17D vaccine downstream from a cytomegalovirus (CMV) promoter. The vaccine was designed to transcribe the full-length viral RNA and to launch 17D vaccine virus in vitro and in vivo. Transfection with 10ng of iDNA plasmid was sufficient to start replication of vaccine virus in vitro. Safety of the parental 17D and iDNA-derived 17D viruses was confirmed in AG129 mice deficient in receptors for IFN-α/β/γ. Finally, direct vaccination of BALB/c mice with a single 20µg dose of iDNA plasmid resulted in seroconversion and elicitation of virus-specific neutralizing antibodies in animals. We conclude that iDNA immunization approach combines characteristics of DNA and attenuated vaccines and represents a promising vaccination strategy for YF.

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“…Phylogenetic studies have revealed that these early CHIKV strains form three major, geographically distinct lineages: the West African enzootic, East/Central/South African (ECSA) enzootic, and Asian endemic/epidemic lineages (11). The enzootic lineages involve sylvatic transmission by arboreal Aedes mosquitoes among nonhuman primates with occasional spillover to humans, while the endemic/epidemic lineages are transmitted human to human by A. aegypti and, recently, A. albopictus mosquitoes in peridomestic settings (10,12). Bayesian coalescent analysis has estimated that the Asian and ECSA lineages diverged about 100 years ago, although it is unclear exactly when the Asian lineage was introduced from Africa (13).…”

mentioning

confidence: 99%

Comprehensive Genome Scale Phylogenetic Study Provides New Insights on the Global Expansion of Chikungunya Virus

Chen

Puri

Fedorova

et al. 2016

J Virol

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Since the India and Indian Ocean outbreaks of 2005 and 2006, the global distribution of chikungunya virus (CHIKV) and the locations of epidemics have dramatically shifted. First, the Indian Ocean lineage (IOL) caused sustained epidemics in India and has radiated to many other countries. Second, the Asian lineage has caused frequent outbreaks in the Pacific islands and in 2013 was introduced into the Caribbean, followed by rapid spread to nearly all of the neotropics. Further, CHIKV epidemics, as well as exported cases, have been reported in central Africa after a long period of perceived silence. To understand these changes and to anticipate the future of the virus, the exact distribution, genetic diversity, transmission routes, and future epidemic potential of CHIKV require further assessment. To do so, we conducted the most comprehensive phylogenetic analysis to date, examined CHIKV evolution and transmission, and explored distinct genetic factors associated with the emergence of the East/Central/ South African (ECSA) lineage, the IOL, and the Asian lineage. Our results reveal contrasting evolutionary patterns among the lineages, with growing genetic diversities observed in each, and suggest that CHIKV will continue to be a major public health threat with the potential for further emergence and spread. IMPORTANCE Chikungunya fever is a reemerging infectious disease that is transmitted by

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Urbanization and geographic expansion of zoonotic arboviral diseases: mechanisms and potential strategies for prevention

Cited by 188 publications

References 15 publications

Zika Virus Infection: Current Concerns and Perspectives

Zika Virus Infection: Current Concerns and Perspectives

Plasmid DNA initiates replication of yellow fever vaccine in vitro and elicits virus-specific immune response in mice

Comprehensive Genome Scale Phylogenetic Study Provides New Insights on the Global Expansion of Chikungunya Virus

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