Uptake of influenza vaccine in ulcerative colitis

Boltin, Doron; Gingold‐Belfer, Rachel; Kimchi, Nimrod A.; Ben‐Bassat, Ofer; Langiewicz, J; Niv, Yaron; Birkenfeld, Shlomo

doi:10.1016/j.vaccine.2014.07.080

Cited by 4 publications

(5 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The first consideration is the “ceiling effect,” which occurs when a high proportion of participants already achieve the study objective, so that variance is no longer easily measured above a certain threshold. Several studies in both the adult [ 20 , 36 , 37 ] and pediatric [ 38 - 40 ] IBD populations have demonstrated lower rates of influenza vaccine uptake than were seen in this study. The uptake of influenza vaccine in the IBD Partners PPRN cohort was already high; therefore, it becomes less likely that any intervention would be significantly better than the standard, text-only intervention, as there is little room for overall measurable improvement in the studied cohort.…”

Section: Discussioncontrasting

confidence: 52%

Web-Based Video Education to Improve Uptake of Influenza Vaccination and Other Preventive Health Recommendations in Adults With Inflammatory Bowel Disease: Randomized Controlled Trial of Project PREVENT

Long¹,

Deen²,

Weisbein³

et al. 2023

J Med Internet Res

View full text Add to dashboard Cite

Background Patients with inflammatory bowel disease (IBD) are at increased risk of infections, bone fractures, and skin cancers. Objective We developed preventive health videos using a patient-centered approach and tested their impact on preventive health uptake. Methods Five animated videos explaining preventive health recommendations in IBD were iteratively developed with patient-centered focus groups and interviews. A randomized controlled trial was then conducted in a web-based IBD cohort to test the impact of video- versus text-based educational interventions. The primary outcome was receipt of the influenza vaccine. Secondary outcomes included intention to receive other preventive health services. Results Five animated videos were developed with patient input. A total of 1056 patients with IBD were then randomized to receive the video (n=511) or text-only (n=545) interventions; 55% (281/511) of the video group and 57% (311/545) of the text-only group had received their influenza vaccine in the prior year. Immediately after the intervention, 73% (502/683) of patients reported their intention to receive the vaccine, with no difference by the type of intervention (75%, 231/307, for the video group and 72%, 271/376, for the text-only group). The proportion of patients who actually received the influenza vaccine after the intervention also did not differ by messaging type (P=.07). The strongest predictor of both intention to receive and actual receipt of the influenza vaccine was prior influenza vaccination. Older age was also associated with a higher likelihood of the intention to receive (age 36-75 years relative to 18-35 years; P=.006) and actual receipt (age >75 years relative to 18-35 years; P=.05) of the influenza vaccine. Conclusions The proportion of patients receiving the influenza vaccine was high in both groups, but there was no difference in receipt of or in the intention to receive preventive health recommendations by type of messaging. Notably, a portion of patients in both groups had intended to be vaccinated but did not ultimately receive the vaccine. Further evaluation of patient-education strategies is warranted to improve preventive health uptake among patients with IBD. Trial Registration ClinicalTrials.gov NCT05997537; https://clinicaltrials.gov/ct2/show/NCT05997537

show abstract

Section: Discussioncontrasting

confidence: 52%

Web-Based Video Education to Improve Uptake of Influenza Vaccination and Other Preventive Health Recommendations in Adults With Inflammatory Bowel Disease: Randomized Controlled Trial of Project PREVENT

Long¹,

Deen²,

Weisbein³

et al. 2023

J Med Internet Res

View full text Add to dashboard Cite

show abstract

“…These findings are consistent with those for the Canadian general population 35 and earlier studies in immunemediated disease populations. 3,36,37 Factors contributing to low vaccination rates include a lack of perceived susceptibility to influenza, lack of perceived severity of infection and lack of belief in the vaccine's effectiveness. 2,3,[47][48][49] Interventions to improve vaccination rates in populations of persons with immune-mediated disease have been tested.…”

Section: Discussionmentioning

confidence: 99%

“… 36 Findings were similar among persons with ulcerative colitis. 37 Reported uptake of influenza vaccine has also ranged widely among persons with rheumatoid arthritis, 5 , 38 – 40 from 26.6% in a German outpatient clinic 40 to 85% in specialty rheumatology centres in the United Kingdom. 5 Comparable findings for multiple sclerosis are more limited.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Uptake of influenza vaccination among persons with inflammatory bowel disease, multiple sclerosis or rheumatoid arthritis: a population-based matched cohort study

Marrie

Walld

Bolton

et al. 2021

cmajo

View full text Add to dashboard Cite

I ndividuals affected by immune-mediated inflammatory diseases (referred to hereafter as immune-mediated diseases), such as inflammatory bowel disease, multiple sclerosis and rheumatoid arthritis, share an increased risk for influenza and related complications; 1 therefore, prevention of influenza is important. Effective implementation of influenza vaccination strategies requires knowledge of vaccine uptake or use among target populations. However, our understanding of influenza vaccine uptake in populations with immune-mediated diseases has been limited by studies with small sample sizes, selection bias, cross-sectional designs, variable study durations and variable study periods. Prior findings regarding vaccine uptake among persons with immune-mediated diseases have been highly variable. 2-5 A

show abstract

“…2 studies assessed the relationship between comorbidity and vaccination with opposite results. One study [30] identified cardiovascular risk as a positive predictor of influenza vaccination, while the other [42] reported that patients with a higher Charlson comorbidity index were less likely to be vaccinated with herpes zoster (live attenuated) vaccine.…”

Section: Predictors Of Vaccinationmentioning

confidence: 99%

Vaccinations and inflammatory bowel disease – a systematic review

Chan¹,

Salazar²,

Lim³

et al. 2021

Digestive and Liver Disease

View full text Add to dashboard Cite

Introduction: Patients with inflammatory bowel disease(IBD) are at risk of infections, many of which are preventable with vaccinations. We performed a systematic review on various aspects of vaccination in IBD. Methods: We searched PubMed, and EMBASE databases, through 31 January 2021. Primary outcomes included vaccination rates, predictors of vaccination, reasons of vaccination hesitancy and acceptance, and outcomes of intervention. Findings were presented with medians, ranges, and narrative synthesis. Results: We included 33 observational studies comprising 146,918 patients and 681 physicians. The median vaccination rates of influenza, pneumococcal pneumonia, and hepatitis B vaccines were 42%(IQR, 28%-61.5%), 20%(IQR, 9%-38.5%), and 48%(IQR, 29%-53%), respectively. Uses of immunosuppressant, older age and physician recommendations have positive influence on vaccination rate. Lack of vaccine-related knowledge and awareness of need for vaccination are main reasons of vaccine hesitancy among patients and physicians. There was disagreement between gastroenterologists and primary-care physicians on whose responsibility to offer vaccination. Education was the sole intervention identified, with variable success. Conclusion:This systematic review demonstrates that the vaccination rates of IBD patients, similar to other chronic diseases, are suboptimal. Lack of vaccine-related knowledge and awareness of the need for vaccination are main reasons of vaccine hesitancy amongst patients and physicians. Education, though effective, was the only available intervention identified. Gastroenterologist could take the lead in educating, and initiating vaccination among IBD patients.

show abstract

Uptake of influenza vaccine in ulcerative colitis

Cited by 4 publications

References 20 publications

Web-Based Video Education to Improve Uptake of Influenza Vaccination and Other Preventive Health Recommendations in Adults With Inflammatory Bowel Disease: Randomized Controlled Trial of Project PREVENT

Web-Based Video Education to Improve Uptake of Influenza Vaccination and Other Preventive Health Recommendations in Adults With Inflammatory Bowel Disease: Randomized Controlled Trial of Project PREVENT

Uptake of influenza vaccination among persons with inflammatory bowel disease, multiple sclerosis or rheumatoid arthritis: a population-based matched cohort study

Vaccinations and inflammatory bowel disease – a systematic review

Contact Info

Product

Resources

About