Uptake of aromatic compounds by DNA: Toward the environmental application of DNA for cleaning water

DNA Nanogels To Snare Carcinogens: A Bioinspired Generic Approach with High Efficiency

“…[18] Since DNAwidely exists in the natural world and can be mass-produced from waste material of the fishing industry such as fish milts,and since we did not find an indication that particle size or dispersity is an important factor for samples with similar DNAc ontent and conformation (% ssDNAp ortion), the particles can be prepared from cheap raw materials using simple and technologically established processes.D NA nanogels or microgels could thus be useful as as cavenging matrix in filters or between membranes,not only for the removal of PA Hs from water but for amore generic detoxification of drinking water. Beyond PA Hb inding,r ecent studies suggest that DNAh as abroader capacity for the removal of hydrophobic toxins that act through DNAi nteraction.…”

“…[14][15][16] This binding is generic,a nd broader and better PA Hb inding has been shown for DNAc ompared to cyclodextrins. [18] Chemically cross-linked DNAh ydrogels present an interesting new class of materials, [19][20][21] and they have,f or example,r ecently been explored as drug-delivery systems. [18] Chemically cross-linked DNAh ydrogels present an interesting new class of materials, [19][20][21] and they have,f or example,r ecently been explored as drug-delivery systems.…”

Intramolecularly Protein-Crosslinked DNA Gels: New Biohybrid Nanomaterials with Controllable Size and Catalytic Activity

“…Besides its biological importance, DNA can be seen as a material that combines unique properties of biocompatibility and programmability . For instance, the use of DNA as a backbone for hydrogels has recently led to various fundamental studies and applications, such as molecular detection, drug or gene delivery, cell culture, and water detoxification . Such DNA hydrogels can be prepared by several methods, including covalent crosslinking between double‐stranded DNA molecules, i‐motif formation or hybridization between sticky ends of branched DNA nanostructures, and physical entangling between long DNA strands .…”

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5] For instance, the use of DNA as a backbone for hydrogels has recently led to various fundamental studies [6][7][8] and applications, [9][10][11] such as molecular detection, [12] drug or gene delivery, [13,14] cell culture, [15] and water detoxification. [16,17] Such DNA hydrogels can be prepared by several methods, including covalent crosslinking between double-stranded DNA molecules, [18] i-motif formation or hybridization between sticky ends of branched DNA nanostructures, [6,[19][20][21] and physical entangling between long DNA strands. [22] For nanotechnological and biomedical applications, the reduction of the dimensions [23][24][25] of such biocompatible materials is often a requisite, which has triggered a growing interest for nano-and microsized DNA gels.

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“…Moreover, the functionality of DNA micro-and nanogels reported so far has been mainly limited to the inherent physicochemical characteristics of their main constituent, that is, DNA. [14,16,17] By contrast, other types of nanogels, such as organic nanogels, have been demonstrated as versatile and useful hosts for functional entities, such as proteins. [24,25,[30][31][32] Finding ways to functionalize DNA nanogels, for instance, with proteins, thus appears as a valuable challenge.…”