Uptake and release of chlorhexidine by bovine pulp and dentin specimens and their subsequent acquisition of antibacterial properties

In vitro effectiveness of different endodontic irrigants on the reduction of Enterococcus faecalis in root canals

“…# Fisher's Exact Test (2-tailed) was used to identify the significant groups at 5% level. of obtaining higher success rates in root canal therapy due to greater reduction in microorganisms (5). The results of the present study are in agreement with other studies (6,15) which showed CHX to be as effective as antimicrobial agent as NaOCl, in vitro.…”

“…(Table 2) Discussion E. faecalis, a facultative gram-positive anaerobe, has been implicated in persistent root canal infections (3,4). It is well recognized as a pathogen associated with persistent apical periodontitis in endodontically treated teeth, easy to culture and has been used successfully in several studies on the efficacy of endodontic irrigants (1,(5)(6)(7). Various studies reported the use of paper points for collecting microbiological samples from the root canals (8)(9)(10).…”

Bacterial Leakage in Roots Filled With Different Medicaments and Sealed With Cavit

“…This may be a result of the fact that dentin reduces the disinfecting effect of CHX to a certain extent (24). Furthermore, a substantivity effect as discussed in earlier studies could not be confirmed by this study (25,26).…”

Root Canal Irrigants

“…Chlorhexidine appears to be the most promising agent to be used as a final irrigant in this situation. It has an affinity to dental hard tissues (154), and once bound to a surface, has prolonged antimicrobial activity, a phenomenon called substantivity (155,156). Substantivity is not observed with sodium hypochlorite (157).…”