Nitrogen is a structural component of chlorophyll and protein therefore adequate supply of nitrogen is beneficial for both carbohydrates and protein metabolism as it promotes cell division and cell enlargement, resulting in more leaf area and thus ensuring good seed and dry matter yield. The experiment entitled effect of nitrogen and phosphorus on yield and yield components of sesame were conducted at New Developmental Farm of the University of Agriculture Peshawar during kharif ( June 2013). Randomized complete block design (RCBD) having four replications were used. Nitrogen and phosphorus levels (0, 30, 60, 90 kg ha -1 ) each were applied in the form of P2O5 from DAP and urea respectively. The whole of phosphorus was applied during seed bed preparation and nitrogen in two splits, half at sowing and half after 80% emergence. The seed rate 4 kg ha -1 of sesame (ocal black) was planted on 28 th June 2013. Total of 3 irrigations were applied, and other cultural practices were kept uniform for all the treatments. Highest number of pods plant -1 (67), number of seeds pods -1 (54), grain yield (520 kg), biological yield (2539 kg), thousand seeds weight (3.91 g) and harvest index (24%) were recorded when higher dose of N i.e. 90 kg ha -1 were used. Similarly enhanced lowest number of pods plant -1 (55), number of seeds pods -1 (50), grain yield (442 kg), biological yield (1570 kg), thousand seed weight (2.94 g), and harvest index (20%) were recorded in control plots. Application of phosphorous has significantly affected seeds pod -1 , and biological yield. Whereas 90 kg P ha -1 increased plant tallness, pods plant -1 , grains yield, thousand seeds weight and harvest index (%). The interaction was non-significant for all studied parameters. Therefore, it was concluded from the results that using nitrogen @ of 90 kg ha -1 with 90 kg P ha -1 have improved the yield and yield components of sesame. Thus the application of 90 kg N ha -1 with 90 kg P ha -1 is recommended for general cultivation in agro-climatic condition of Peshawar valley.