Abstract:Myocardial ischemia and hypoxia are one of the main causes of heart
failure, and cardiomyocyte apoptosis induced by mitochondrial injury is
the basis of poor heart remodeling and heart failure. Upstream
stimulatory factor 2 (USF2), a transcription factor involved in multiple
cellular processes, has recently been identified as having an active
role in mitochondrial function and energy homeostasis; however, the role
of USF2 in cardiovascular disease has not been reported. In this study,
we demonstrated that the … Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.