Upper respiratory problems in the Yellow Nail Syndrome

M, Morán; Larkworthy, William

doi:10.1111/j.1365-2273.1976.tb00654.x

Cited by 11 publications

(2 citation statements)

References 2 publications

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“…One hundred and twelve studies involving 150 patients were selected for review, spanning a period of nearly 50 years. Figure presents a flow chart for the complete breakdown in the identification of appropriate studies . They all corresponded to the description of isolated case reports (between 1 and 4 per item) and a retrospective series of 19 patients…”

Section: Resultsmentioning

confidence: 99%

Characteristics of patients with yellow nail syndrome and pleural effusion

et al. 2014

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Yellow nail syndrome (YNS) can be associated with a pleural effusion (PE) but the characteristics of these patients are not well defined. We performed a systematic review across four electronic databases for studies reporting clinical findings, PE characteristics, and most effective treatment of YNS. Case descriptions and retrospective studies were included, unrestricted by year of publication. We reviewed 112 studies (150 patients), spanning a period of nearly 50 years. The male/female ratio was 1.2/1. The median age was 60 years (range: 0-88). Seventy-eight percent were between 41-80 years old. All cases had lymphoedema and 85.6% had yellow nails. PEs were bilateral in 68.3%. The appearance of the fluid was serous in 75.3%, milky in 22.3% and purulent in 3.5%. The PE was an exudate in 94.7% with lymphocytic predominance in 96% with a low count of nucleated cells. In 61 of 66 (92.4%) of patients, pleural fluid protein values were >3 g/dL, and typically higher than pleural fluid LDH. Pleurodesis and decortication/pleurectomy were effective in 81.8% and 88.9% of cases, respectively, in the treatment of symptomatic PEs. The development of YNS and PE occurs between the fifth to eighth decade of life and is associated with lymphoedema. The PE is usually bilateral and behaves as a lymphocyte-predominant exudate. The most effective treatments appear to be pleurodesis and decortication/pleurectomy.

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Section: Resultsmentioning

confidence: 99%

Characteristics of patients with yellow nail syndrome and pleural effusion

et al. 2014

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“…Successful treatment of the sinusitis with a potassium-sparing diuretic has been described in one patient (Moran and Larkworthy, 1976). About 25 per cent of patients in the literature are noted to have had sinusitis as part of the yellow nail syndrome and the high incidence of recurrent sinus surgery in this group suggests a poor response to this form of management.…”

Section: Reviewmentioning

confidence: 99%

Chronic sinusitis and the yellow nail syndrome

1990

J. Laryngol. Otol.

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Diagnosing syndromes that include chronic sinusitis can expedite the management of both conditions. Yellow nail syndrome is usually described as the combination of yellow nails, lymphoedema and often respiratory manifestations such as chronic sinusitis, bronchiectasis and pleural effusions. The pathology responsible for the syndrome is believed to be lymphatic hypoplasia. Diagnosis of yellow nail syndrome is clinical not requiring any specialized tests. In the two cases described, the respiratory tract manifestations required the most active investigation and management. The significance of this syndrome to the otolaryngologist is discussed.

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The Nail in Systemic Disease

Holzberg

2012

Baran &Amp; Dawber's Diseases of the Nails and Their Management

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Upper respiratory problems in the Yellow Nail Syndrome

Cited by 11 publications

References 2 publications

Characteristics of patients with yellow nail syndrome and pleural effusion

Characteristics of patients with yellow nail syndrome and pleural effusion

Chronic sinusitis and the yellow nail syndrome

The Nail in Systemic Disease

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