Upper Limb Ischemia Due to Arterial Thrombosis after COVID-19 Vaccination

Alsmady, Moaath; Al-Qaryouti, Rahaf A; Sultan, Nesrin G; Khrais, Oweis I; Khrais, Huthaifah

doi:10.1155/2022/4819131

Cited by 3 publications

(2 citation statements)

References 18 publications

(32 reference statements)

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“…Subsequently, the patient sought medical attention, reporting symptoms of discomfort and abnormal sensations in the left hand. The presence of upper limb ischemia was identified using investigative measures [161].…”

Section: Summary Of Reported Literature Cases Of Ultrarare Vitt Compl...mentioning

confidence: 99%

Blood Coagulation and Thrombotic Disorders following SARS-CoV-2 Infection and COVID-19 Vaccination

Sekulovski,

Mileva,

Vasilev

et al. 2023

Biomedicines

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Although abundant data confirm the efficacy and safety profile of the developed vaccines against COVID-19, there are still some concerns regarding vaccination in high-risk populations. This is especially valid for patients susceptible to thrombotic or bleeding events and hesitant people due to the fear of thrombotic incidents following vaccination. This narrative review focuses on various inherited and acquired thrombotic and coagulation disorders and the possible pathophysiologic mechanisms interacting with the coagulation system during immunization in view of the currently available safety data regarding COVID-19 vaccines. Inherited blood coagulation disorders and inherited thrombotic disorders in the light of COVID-19, as well as blood coagulation and thrombotic disorders and bleeding complications following COVID-19 vaccines, along with the possible pathogenesis hypotheses, therapeutic interventions, and imaging for diagnosing are discussed in detail. Lastly, the lack of causality between the bleeding and thrombotic events and COVID-19 vaccines is debated, but still emphasizes the importance of vaccination against COVID-19, outweighing the minimal risk of potential rare adverse events associated with coagulation.

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Section: Summary Of Reported Literature Cases Of Ultrarare Vitt Compl...mentioning

confidence: 99%

Blood Coagulation and Thrombotic Disorders following SARS-CoV-2 Infection and COVID-19 Vaccination

Sekulovski,

Mileva,

Vasilev

et al. 2023

Biomedicines

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“…If the patient is showing progression of thrombosis or the platelet count fails to rise, options include further doses of IVIg, corticosteroids, plasma exchange, and rituximab [21]. Alongside the medical management, the surgical treatment of thrombosis in VITT includes embolectomy/ thrombectomy, fasciotomy, or amputation (which occurred in Case 1), as has been described in several other cases [22][23][24][25].…”

Section: E Management Of Vitt and "Vaccine-associated Itp" At Our Centrementioning

confidence: 99%

A Single-Centre Experience of Post-COVID-19 Vaccine-Related Immune-Mediated Complications

Palmer

Davis

Sivaloganathan

et al. 2022

Case Reports in Hematology

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The significant impact of the COVID-19 pandemic has resulted in a worldwide effort to develop effective vaccines. In the United Kingdom, the COVID-19 vaccine development and roll-out has been overwhelmingly successful in reducing infections and deaths. However, case reports have emerged of a rare syndrome of vaccine-induced immune thrombocytopenia and thrombosis (VITT), as well as cases of immune thrombocytopenia (ITP). This has necessitated a better understanding of these conditions. However, as both VITT and “vaccine-associated ITP” are emerging conditions, evidence on the clinical features, epidemiology, and management is still evolving. Subsequently, with the initiation of the COVID-19 vaccine booster program, it has become increasingly important to continue to collect accurate data on post-COVID-19 vaccine complications to aid with their prompt recognition and management. In this case series, we report on the presentations and management of seven cases of post-COVID-19 vaccine-related immune-mediated complications which occurred at our center between the months of March and July 2021.

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Azd-1222

2024

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Upper Limb Ischemia Due to Arterial Thrombosis after COVID-19 Vaccination

Cited by 3 publications

References 18 publications

Blood Coagulation and Thrombotic Disorders following SARS-CoV-2 Infection and COVID-19 Vaccination

Blood Coagulation and Thrombotic Disorders following SARS-CoV-2 Infection and COVID-19 Vaccination

A Single-Centre Experience of Post-COVID-19 Vaccine-Related Immune-Mediated Complications

Azd-1222

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