Upper gastrointestinal endoscopy findings in patients with long-standing bulimia nervosa

Kiss, Alexander; Wiesnagrotzki, Stefan; Abatzi, Thalia-Anthi; Meryn, Siegfried; Haubenstock, Alexander; Base, Wolfgang

doi:10.1016/s0016-5107(89)72901-1

Cited by 37 publications

(18 citation statements)

References 4 publications

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“…Genuine GI complications are rare, particularly compared with the other types of complications encountered in bulimia nervosa (e.g., electrolyte abnormalities, dental erosion; Mitchell et al, 1991), are typically related directly to purging behavior (Waldholtz, 1999), and can be quite serious (Mitchell et al, 1991). These may include erythema of the stomach mucosa (Kiss et al, 1989), esophagitis (Cuellar, Kaye, Hsu, & Van Thiel, 1988), upper GI bleeding (Robinson, 2000), perforation of the esophagus (De Caprio, Pasanisi, & Contaldo, 2000), gastric dilatation and rupture (Alvin, Zogheib, Rey, & Losay, 1993;Deret et al, 1987;Holtkamp, Mogharrebi, Hanisch, Schumpelick, & Herpertz-Dahlmann, 2002;Jacquot, Lamy, Cohen, & Le Quintree, 1989;Koyazounda et al, 1985;Mitchell, Pyle, & Miner, 1982;Qin, Yao, & Zhang, 2000;Reeve, Jackson, Scott-Connor, & Sledge, 1988;Seligmann, Liehr, & Schwarz, 1998), gastric necrosis (Anderson, Shaw, & McCargar, 1997), and possibly gastric cancer, which may be secondary to the epithelial changes of Barrett's esophagus (Walker, 1985).…”

Section: Discussionmentioning

confidence: 99%

An unusual cause of dizziness in bulimia nervosa: A case report

Sansone

Naqvi

Sansone

2005

Int. J. Eat. Disord.

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Section: Discussionmentioning

confidence: 99%

An unusual cause of dizziness in bulimia nervosa: A case report

Sansone

Naqvi

Sansone

2005

Int. J. Eat. Disord.

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“…The repeated exposure of the esophagus to stomach acid causes irritation and/or damage to the mucosal wall lining. In a study of patients with bulimia nervosa, a quarter of the patients had mild esophagitis and symptoms of gastroesophageal reflux, frequent retrosternal burning (heartburn), and acid regurgitation . Another 16% of those patients had superficial mucosal erythema in the stomach or duodenum (red and irritated lining).…”

Section: Self‐induced Vomitingmentioning

confidence: 99%

“…In a study of patients with bulimia nervosa, a quarter of the patients had mild esophagitis and symptoms of gastroesophageal reflux, frequent retrosternal burning (heartburn), and acid regurgitation. 54 Another 16% of those patients had superficial mucosal erythema in the stomach or duodenum (red and irritated lining). The presence of these symptoms was not associated with the duration or severity of purging behavior.…”

Section: Esophagus and Stomachmentioning

confidence: 99%

The medical complications associated with purging

Forney

Buchman‐Schmitt

Keel

et al. 2016

Intl J Eating Disorders

102

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Objective Purging behaviors, including self-induced vomiting, laxative abuse, and diuretic abuse, are present across many of the eating disorders. Here we review the major medical complications of these behaviors. Method Although we identified over 100 scholarly articles describing medical complications associated with purging, most papers involved case studies or small, uncontrolled samples. Given the limited evidence base, we conducted a qualitative (rather than systematic) review to identify medical complications that have been attributed to purging behaviors. Results Medical conditions affecting the teeth, esophagus, gastrointestinal system, kidneys, skin, cardiovascular system, and musculoskeletal system were identified, with self-induced vomiting causing the most medical complications. Conclusions Purging behavior can be associated with severe medical complications across all body systems. Mental health professionals should refer patients with purging behaviors to medical providers for screening and treatment as needed. The medical work-up for individuals with eating disorders should include a comprehensive metabolic panel, complete blood count, and a full body exam including the teeth to prevent severe complications. Medical providers should screen patients for purging behaviors and associated medical complications, even in the absence of an eating disorder diagnosis, to increase the detection of eating disorders. Recognizing the link between purging and medical complications can aid in identifying potential eating disorders, particularly those that often elude detection such as purging disorder.

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“…Furthermore, laxative abuse in these patients can result in alterations in pancreatic function [121], diarrhea [122,123], melanosis coli [124], renal failure [125] and urinary tract stones [126]. Manometry and upper endoscopy studies in patients unwell with bulimia have [127] and have not [128,129] found disordered motility or esophagitis to be common.…”

Section: Gastrointestinal Diseasementioning

confidence: 99%

The Long Term Biological Consequences of Anorexia Nervosa

Gendall¹,

Bulik²

2005

CNF

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The long-term psychiatric and psychological outcome of the anorexia nervosa (AN) has been well described. Less is known about the long-term physiological effects of the illness and this article reviews the findings to date. Having a history of AN does not appear to increase the risk of infertility, but may increase the risk of birth complications and of having a low birth weight infant. Although evidence on the reversibility of bone mineral density loss in AN is conflicting, osteoporosis-related fracture rates are higher in women with previous AN. Animal models of energy restriction and two studies in AN suggest that AN may confer protection against breast cancer, however data are preliminary. Furthermore, it is theoretically possible, that deficiencies of chemoprotective nutrients, chronic constipation, laxative abuse, and selfinduced vomiting may increase the risk of other, and in particular, gastrointestinal tract, pathology. This risk remains to be investigated. The metabolic and endocrine effects of the illness are largely reversed with recovery, but various disturbances in pancreatic hormone secretion have been described and require further clarification. As cohorts of women with a history of AN mature, well controlled studies are recommended to provide further information on the long-term health consequences of AN.

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Upper gastrointestinal endoscopy findings in patients with long-standing bulimia nervosa

Cited by 37 publications

References 4 publications

An unusual cause of dizziness in bulimia nervosa: A case report

An unusual cause of dizziness in bulimia nervosa: A case report

The medical complications associated with purging

The Long Term Biological Consequences of Anorexia Nervosa

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