Upper Gastrointestinal Bleeding From Metastatic Testicular Cancer

Laiyemo, Adeyinka O.; Jack, Momodu; Dawkins, Fitzroy W.; Smoot, Duane T.

doi:10.1016/s0027-9684(15)31011-7

Cited by 2 publications

(1 citation statement)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Gastrointestinal symptoms can also be the first symptom of recurrence in patients with previously treated GCT. GCT presenting as abdominal pain with finding of polypoid masses in the gastrointestinal tract within 2 years of orchiectomy and chemotherapy have been reported [ 14 , 15 ].…”

Section: Discussionmentioning

confidence: 99%

Gastrointestinal Involvement of Testicular Germ Cell Tumor: A Case Report and Literature Review

Shogbesan

Abdulkareem

Jehangir

et al. 2017

Case Reports in Gastrointestinal Medicine

View full text Add to dashboard Cite

Testicular germ cell tumors (GCT) are the commonest solid tumors in young men. Typical presentation is with painless scrotal swelling; however, symptoms related to complications or metastasis may be the initial presentation. Gastrointestinal (GI) metastasis is seen in about 5% of patients with germ cell tumors and presentation is commonly with GI bleed. It is important to have GCT as a differential diagnosis of GI bleed in young men presenting with unexplained anemia as direct questioning about scrotal swelling and genital examination when appropriate will guide further investigation and facilitate prompt diagnosis. We present a case of a 26-year-old man with testicular germ cell tumor and severe anemia secondary to extension and perforation of duodenum by retroperitoneal metastasis and a review of the literature on the gastrointestinal manifestations of testicular germ cell tumors.

show abstract

Section: Discussionmentioning

confidence: 99%

Gastrointestinal Involvement of Testicular Germ Cell Tumor: A Case Report and Literature Review

Shogbesan

Abdulkareem

Jehangir

et al. 2017

Case Reports in Gastrointestinal Medicine

View full text Add to dashboard Cite

show abstract

Germ Cell Cancer Presenting as Gastrointestinal Bleeding and Developing Brain Metastases: Case Report and Review of the Literature

Fu¹,

Avezbakiyev²,

Zhi³

et al. 2012

Future Oncol.

View full text Add to dashboard Cite

This paper describes a rare case of germ cell cancer with duodenum, brain and lung metastases. The patient presented with melena and left testicle enlargement. Orchiectomy revealed mixed germ cell cancer, enteroscopy revealed duodenal choriocarcinoma, and chest x-ray and computed tomography (CT) showed bilateral lung metastases. The patient received and tolerated cisplatinum-based chemotherapy, and responded well. However, he developed seizures 3 months later. MRI showed brain metastases and he was treated with whole-brain radiation. One month later, he developed progressive dyspnea. Chest CT showed worsening lung metastases. He received second-line chemotherapy, but died due to multiorgan failure. Germ cell cancer with nonpulmonary metastases has poor prognosis and the management of these patients requires a multimodal approach. Head CT should be considered as routine screening for all germ cell cancer patients on initial diagnosis and brain MRI should be considered for high-risk patients (with an embryo- or choriocarcinoma histology, dramatically elevated β-human chorionic gonadotropin and lung involvement).

show abstract

Upper Gastrointestinal Bleeding From Metastatic Testicular Cancer

Cited by 2 publications

References 8 publications

Gastrointestinal Involvement of Testicular Germ Cell Tumor: A Case Report and Literature Review

Gastrointestinal Involvement of Testicular Germ Cell Tumor: A Case Report and Literature Review

Germ Cell Cancer Presenting as Gastrointestinal Bleeding and Developing Brain Metastases: Case Report and Review of the Literature

Contact Info

Product

Resources

About