Upper extremity versus lower extremity deep venous thrombosis

Hingorani, Anil; Ascher, Enrico; Hanson, Jydith; Scheinman, Marcel; Yorkovich, William; Lorenson, Elke; DePippo, Patrick; Salles-Cunha, Sérgio X.

doi:10.1016/s0002-9610(97)00088-3

Cited by 73 publications

(41 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It must be underlined that UEDVT has been recently associated to higher morbidity and mortality for pulmonary embolism than LEDVT [13]. Furthermore, post-thrombotic sequelae may follow UEDVT [14].…”

Section: Resultsmentioning

confidence: 99%

Congenital and acquired thrombotic risk factors in lymphoma patients bearing upper extremities deep venous thrombosis: a preliminary report

Micco¹,

Niglio²,

Renzo

et al. 2004

J Transl Med

View full text Add to dashboard Cite

BackgroundCongenital thrombotic risk factors, oncological diseases and its therapies have been related to an increased occurrence of upper extremities deep venous thrombosis (UEDVT).Patients and methodsWe studied seven patients bearing lymphoma (one Hodgkin's and six non-Hodgkin's) who developed UEDVT, one at diagnosis and six during chemotherapy (two of these six cases had implantation of a central venous catheter and four received Growth Colony Stimulating Factors in addition to chemotherapy). Patients were screened for: factor V G1691A (Leiden), prothrombin G20210A, methylene tetrahydrofolate reductase (MTHFR) C677T mutations and antithrombin III, proteins C and S plasma activity.ResultsAll patients were wild-type homozygotes for G20210A. One was heterozygote for factor V G1691A, the other 6 were wild-type homozygotes. Three of the 7 patients were homozygotes and 2 heterozygotes for the MTHFR mutation; the remaining 2 were wild-type homozygotes. Clotting inhibitor levels were normal in all patients.ConclusionsUEDVT in patients bearing haematological malignancies can occur irrespective of congenital thrombophilic alterations. However, in a subgroup of patients UEDVT could also depend on congenital thrombophilic alterations. A screening for inherited thrombophilia can identify high risk patients that could be specifically treated to prevent thrombotic complications.

show abstract

Section: Resultsmentioning

confidence: 99%

Congenital and acquired thrombotic risk factors in lymphoma patients bearing upper extremities deep venous thrombosis: a preliminary report

Micco¹,

Niglio²,

Renzo

et al. 2004

J Transl Med

View full text Add to dashboard Cite

show abstract

“…UEDVT was long thought to be a rather harmless and rare event. Recent studies, however, have concluded that pulmonary embolism has a high prevalence among catheter-related UEDVT, fully comparable with that of lower extremity DVT (21,22), and that UEDVT is associated with a morbidity and mortality at least as high as that for lower extremity DVT (23,24), although it appears that the underlying disease process that led to the UEDVT probably contributes to the high mortality, possibly more so than pulmonary embolism.…”

Section: Significance Of Upper Extremity Deep Venous Thrombosismentioning

confidence: 98%

Upper extremity deep venous thrombosis in patients with 5-fluorouracil-containing adjuvant chemotherapy Three Case Reports and a Review

Tham¹,

Albertsson²

2004

Acta Oncologica

View full text Add to dashboard Cite

“…Additionally, of 600 patients with isolated SVT, 10.2% developed thromboembolic complications at 3 months, though 90.5% had been treated with anticoagulants (Decousus et al, 2010). While upper extremity DVT is less common than lower extremity DVT, the risk of PE is high, at 36%, for all upper extremity DVT (Hingorani et al, 1997). While upper extremity DVT is less common than lower extremity DVT, the risk of PE is high, at 36%, for all upper extremity DVT (Hingorani et al, 1997).…”

Section: Epidemiology (With Specific Focus On Neurologic Disease)mentioning

confidence: 99%

Venous thromboembolism in neurologic disease

Schneck

2014

Handbook of Clinical Neurology

View full text Add to dashboard Cite

Upper extremity versus lower extremity deep venous thrombosis

Cited by 73 publications

References 27 publications

Congenital and acquired thrombotic risk factors in lymphoma patients bearing upper extremities deep venous thrombosis: a preliminary report

Congenital and acquired thrombotic risk factors in lymphoma patients bearing upper extremities deep venous thrombosis: a preliminary report

Upper extremity deep venous thrombosis in patients with 5-fluorouracil-containing adjuvant chemotherapy Three Case Reports and a Review

Venous thromboembolism in neurologic disease

Contact Info

Product

Resources

About