Upper airway involvement in pediatric COVID‐19

Parisi, Giuseppe Fabio; Brindisi, Giulia; Indolfi, Cristiana; Diaferio, Lucia; Marchese, Giuseppe; Ghiglioni, Daniele Giovanni; Zicari, Anna Maria; Giudice, Michele Miraglia Del

doi:10.1111/pai.13356

Cited by 28 publications

(31 citation statements)

References 8 publications

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“…From recent reports, Italian pediatric cases (between 0 and 19 years of age) amounted to 518,057, corresponding to 14.1% of all the affected population, with 22 pediatric deaths. SARS-CoV-2 infection in children is less common, often spreads within family clusters, and manifests with mild and varied symptoms [ 4 , 5 ] such as fever, nasal congestion, cough, dyspnea, myalgia, arthralgia, headache, gastrointestinal, and skin manifestations with the characteristic anosmia and ageusia [ 6 , 7 ]. Rare cases have shown severe respiratory symptoms requiring intensive care or a multisystem inflammatory syndrome (MIS-C) [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

Updates on Children with Allergic Rhinitis and Asthma during the COVID-19 Outbreak

Brindisi

Vittori

Nola

et al. 2021

JCM

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Background: During the lockdown period caused by the SARS-CoV-2 pandemic, we monitored via online survey the trend of allergic symptoms and the therapeutic compliance in patients followed at our center. Material and methods: In June 2020, we selected children followed at the Allergy and Immunology Service of Umberto I Hospital, aged between 6 and 16 years old, diagnosed with asthma and/or rhinitis and sensitized to grass pollen or dust mite. We sent an email with 12 multiple-choice questions investigating several areas: type of disease and sensitization, recurrence of symptoms, medication use during lockdown compared to the same period of the previous year. Results: The results of 82 questionnaires showed that 17.8% of patients suffered from asthma, 24.4% from rhinitis, and 57.8% from both. Within the group of asthmatic children, most of them presented an improvement of their symptoms. Likewise, with regard to allergic rhinitis, most of them reported better clinical conditions. Regarding treatment, we observed a global decrease in the use of on-demand therapies (salbutamol, nasal corticosteroid, and antihistamine) for both pathologies. In addition, there was a reduction in the use of basal therapy for asthma and rhinitis from 2019 (23.3%) to 2020 (15.5%). Conclusions: Our data show a general trend of clinical improvement and a reduction in the use of on-demand and basal therapy in allergic children during the lockdown.

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Section: Introductionmentioning

confidence: 99%

Updates on Children with Allergic Rhinitis and Asthma during the COVID-19 Outbreak

Brindisi

Vittori

Nola

et al. 2021

JCM

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“…As for children, the situation is slightly different. In fact, it is known that the course of COVID-19 in children is much less severe than in adults, and more serious complications, such as pneumonia, are less frequent [4][5][6]. However, recent evidence seems to show that long-COVID symptoms also affect younger patients [7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Cross-Sectional Survey on Long Term Sequelae of Pediatric COVID-19 among Italian Pediatricians

et al. 2021

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The persistence of symptoms after recovery from Coronavirus 2019 (COVID-19) is defined as long COVID, an entity that had occurred among adults but which is not yet well characterized in pediatric ages. The purpose of this work was to present some of the data from a survey addressed to Italian pediatricians concerning the impact of long-COVID among children who recovered from severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. The questionnaire was designed and pre-tested in February 2021 by a working group of experts from the Italian Pediatric Society for Allergy and Immunology (SIAIP). The survey was emailed once in March 2021 to a sample of Italian pediatricians. A total 267 Italian pediatricians participated in our survey. According to most pediatricians (97.3%), the persistence of symptoms is found in less than 20% of children. Specifically, with regard to the symptoms that persist even after swab negativization, fatigue was the most mentioned one (75.6%). Long-COVID would seem to be a phenomenon of limited occurrence in pediatric ages, affecting less than 20% of children. Among all of the symptoms, the one that was most prevalent was fatigue, a pathological entity that is associated with many viral diseases.

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“…Lu et al found the main symptoms in 171 children with COVID-19 to be cough (48.5%), pharyngitis (46.2%), fever (41.5%), diarrhea (8.8%), and vomiting (6.4%); only 2.3% of cases experienced desaturation upon hospitalization, while 15.8% of cases were asymptomatic ( 9 ). Olfactory and gustatory anomalies characteristic of adult COVID-19 cases are rare in pediatric populations ( 11 , 12 ).…”

Section: Introductionmentioning

confidence: 99%

COVID-19 Pneumonia in Children: From Etiology to Management

et al. 2020

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COVID-19 is less serious in children than in adults. However, respiratory management dominates the clinical picture of hospitalized COVID-19 even in children. In some case series, deterioration of the clinical picture wherein dyspnea, cyanosis, and the onset of acute respiratory distress syndrome (ARDS) emerged ~8–10 days after the onset of SARS-CoV-2 infection, which could rapidly progress to multiple organ failure and death. This review aimed to evaluate the characteristics of COVID-19 pneumonia in pediatric populations, beginning from its etiology and pathological mechanisms and closing with its clinical management.

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Upper airway involvement in pediatric COVID‐19

Cited by 28 publications

References 8 publications

Updates on Children with Allergic Rhinitis and Asthma during the COVID-19 Outbreak

Updates on Children with Allergic Rhinitis and Asthma during the COVID-19 Outbreak

Cross-Sectional Survey on Long Term Sequelae of Pediatric COVID-19 among Italian Pediatricians

COVID-19 Pneumonia in Children: From Etiology to Management

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