“…We found 21 reports of MR lesions outside the skin and osteoarticular system, 8,10,14–16,21,23–28,30–32,42,44,49,71,73,74,78 13 of them were limiting for the patients 8,14,21,23,26,27,30,31,44,49,71,73,78 …”
Section: Discussionmentioning
confidence: 99%
“…described a unique case with vulvar and perianal lesions. Changes in the voice due to true vocal cords mass of MR may be seen 21 …”
Section: Review Of the Literature (Table 1)mentioning
“…We found 21 reports of MR lesions outside the skin and osteoarticular system, 8,10,14–16,21,23–28,30–32,42,44,49,71,73,74,78 13 of them were limiting for the patients 8,14,21,23,26,27,30,31,44,49,71,73,78 …”
Section: Discussionmentioning
confidence: 99%
“…described a unique case with vulvar and perianal lesions. Changes in the voice due to true vocal cords mass of MR may be seen 21 …”
Section: Review Of the Literature (Table 1)mentioning
“…Otros compromisos detallados son los de la mucosa oral 3,20 , glándulas salivares mayores 4,15 , nódulos submucosos hipofaríngeos 4,21 , nódulos laríngeos 4,22 y nódulos hepáticos 23 . Se han informado casos aislados de RHM con fenómeno de Raynaud y esplenomegalia 4,24 .…”
La reticulohistiocitosis multicéntrica (RHM) es una histiocitosis de células no Langerhans, multisistémica, rara, caracterizada por afectación cutánea y articular, que poco frecuentemente afecta a otros órganos. El diagnóstico se basa en hallazgos clínicos y resultados de biopsias de piel o sinovial, sin describirse un parámetro de laboratorio específico. Realizamos una revisión de la literatura en relación a las características clínicas de esta entidad desde el punto de vista reumatológico.
“…Dysphagia can be present, representing lesions of the esophagus. Researchers have observed a change in the voice caused by a lesion partially obstructing the vocal chords 51 and isolated reports of hoarseness and nasopharyngeal bleeding have been published 52 . Finally, a single case has been reported in which perianal and vulvar lesions were observed 53…”
The authors present part I of a review of multicentric reticulohistiocytosis, a rare systemic proliferative disease of histiocytes of unknown cause. It is clinically characterized by cutaneous and mucosal nodules and by osteoarticular lesions. The disease occurs in outbreaks that progress in severity, with spontaneous regression, but usually leaving incapacitating arthritis and disfiguring facial lesions. The authors discuss the historical, epidemiologic, and clinical aspects of this disease.
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