Upper Abdominal Pain—An Unusual Symptom of Ectopic Pregnancy

Abstract

tional interest was the analysis of sex chromatin distribution and estrogen receptor protein (ERP) in breast carcinomas. Sex chromatin counts were obtained from imprints made directly from the same tumor samples submitted for ERP analysis at the time of biopsy. Substantially lower sex chromatin counts were found in ERP-negative primary tumors than in ERP-positive carcinomas. These results may explain the more favorable prognosis associated with Barr chromatin body-positive breast carcinomas.2 Also, on the basis of this observation, we have specu¬ lated that a gene locus associated with the production or action of ERP is X-linked. Since there appeared to be no consistent relationship between ERP and sex chromatin count in métastases, we considered it possible that interval therapy might have altered the cells and obscured Barr chromatin bodies.