UPLC–MS/MS assay of 21-aminosteroid (lazaroid U74389G) for application in pharmacokinetic study

The hyphenation of ultra-performance liquid performance (UPLC) with mass spectroscopy (MS) has emerged as a powerful tool in analytical research due to its advanced sensitivity, resolution and speed. Its advanced instrumentation, specialized columns, separation at ultra-high pressure and sophisticated software are the distinguishing features as compared to the traditional separating techniques. It has a wide range of applications in various fields such as analysis of food stuffs, drug metabolites, beverages, toxicology, soil samples and micronutrient analysis. In the present compilation, authors have highlighted the applicability of UPLC-MS in the analysis of food stuffs and drug metabolites along with various optimized analytical conditions and obtained results.

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UPLC–MS/MS assay of 21-aminosteroid (lazaroid U74389G) for application in pharmacokinetic study

Cited by 3 publications

References 21 publications

Enhanced brain delivery with lower hepatic exposure of lazaroid loaded nanostructured lipid carriers developed using a design of experiment approach

Enhanced brain delivery with lower hepatic exposure of lazaroid loaded nanostructured lipid carriers developed using a design of experiment approach

Pharmacological inhibition of lipid peroxidative damage by the 21-aminosteroid U-74389G improves cortical mitochondrial function following traumatic brain injury in young adult male rats

Impact of UPLC-MS in Food and Drug/Metabolite Analysis

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