“…The stage III cohort generally consisted of multiple histological types with a majority of squamous cell carcinoma and adenocarcinoma patients, except for 2 studies which consisted solely of adenocarcinoma [17] or squamous cell carcinoma [51] patients and 10 studies in which histological type was not reported specifically for stage III patients [14,31,33,35,39,74] or at all [20,50,64,70]. Stage III patients were treated exclusively with chemotherapy and/or radiotherapy in 39 studies [11-13,15,18,20,21,31,32,34-36,41,45,47,48 ,51,53-56,58-60,64,65,67,70-72,74,76,77,80-85], while surgery was an option in 25 publications [14,16,17,33,[37][38][39][40][42][43][44]46,49,50,52,57,[61][62][63]66,68,73,75,78,79]. A single study did not report treatment modalities [69].…”