Updates on Recent Developments in Idiopathic Intracranial Hypertension

Peng, Micalla G.; Gokoffski, Kimberly K.

doi:10.1007/s42399-021-00814-6

Cited by 10 publications

(10 citation statements)

References 89 publications

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“…IIH is metabolic disease defined by raised intracranial pressure (ICP) and papilledema of unknown aetiology [24][25][26][27][28]. IIH is a rare disease, affecting 4.69 per 100,000 in the general population, where the incidence is increasing in line with the increasing incidence of obesity [29].…”

Section: Idiopathic Intracranial Hypertension: Epidemiology Features and Treatmentsmentioning

confidence: 99%

Understanding the link between obesity and headache- with focus on migraine and idiopathic intracranial hypertension

et al. 2021

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Background Obesity confers adverse effects to every system in the body including the central nervous system. Obesity is associated with both migraine and idiopathic intracranial hypertension (IIH). The mechanisms underlying the association between obesity and these headache diseases remain unclear. Methods We conducted a narrative review of the evidence in both humans and rodents, for the putative mechanisms underlying the link between obesity, migraine and IIH. Results Truncal adiposity, a key feature of obesity, is associated with increased migraine morbidity and disability through increased headache severity, frequency and more severe cutaneous allodynia. Obesity may also increase intracranial pressure and could contribute to headache morbidity in migraine and be causative in IIH headache. Weight loss can improve both migraine and IIH headache. Preclinical research highlights that obesity increases the sensitivity of the trigeminovascular system to noxious stimuli including inflammatory stimuli, but the underlying molecular mechanisms remain unelucidated. Conclusions This review highlights that at the epidemiological and clinical level, obesity increases morbidity in migraine and IIH headache, where weight loss can improve headache morbidity. However, further research is required to understand the molecular underpinnings of obesity related headache in order to generate novel treatments.

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Section: Idiopathic Intracranial Hypertension: Epidemiology Features and Treatmentsmentioning

confidence: 99%

Understanding the link between obesity and headache- with focus on migraine and idiopathic intracranial hypertension

et al. 2021

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“…regardless of the reason for the consultation) physician contacts was also significantly lower in the IC group, a reduction in costs can also be expected in addition to the obvious benefits for the quality of life of patients and the relief of emergency rooms and other structures that lack specialization for IIH. However, the costs associated with IIH management can vary widely depending on factors such as the severity of the condition, the individual patient’s needs, geographic location, healthcare system, insurance coverage, and specific treatment approaches [ 7 , 28 , 29 ]. In our practice, the one-stop outpatient clinic essentially assumed a hub function for IIH patients in the healthcare sector in the sense of a “quasi general practitioner”.…”

Section: Discussionmentioning

confidence: 99%

An interdisciplinary integrated specialized one-stop outpatient clinic for idiopathic intracranial hypertension – an assessment of sick leave, presenteeism, and health care utilization

Bsteh,

Macher,

Krajnc

et al. 2024

J Headache Pain

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Background Management of idiopathic intracranial hypertension (IIH) is complex requiring contributions from multiple specialized disciplines. In practice, this creates considerable organizational and communicational challenges. To meet those challenges, we established an interdisciplinary integrated outpatient clinic for IIH with a central coordination and a one-stop- concept. Here, we aimed to evaluate effects of this concept on sick leave, presenteeism, and health care utilization. Methods In a retrospective cohort study, we compared the one-stop era with integrated care (IC, 1-JUL-2021 to 31-DEC-2022) to a reference group receiving standard care (SC, 1-JUL-2018 to 31-DEC-2019) regarding economic outcome parameters assessed over 6 months. Multivariate binary logistic regression models were used to adjust for confounders. Results Baseline characteristics of the IC group (n = 85) and SC group (n = 81) were comparable (female: 90.6% vs. 90.1%; mean age: 33.6 vs. 32.8 years, educational level: ≥9 years of education 60.0% vs. 59.3%; located in Vienna 75.3% vs. 76.5%). Compared to SC, the IC group showed significantly fewer days with sick leave or presenteeism (-5 days/month), fewer unscheduled contacts for IIH-specific problems (-2.3/month), and fewer physician or hospital contacts in general (-4.1 contacts/month). Subgroup analyses of patients with migration background and language barrier consistently indicated stronger effects of the IC concept in these groups. Conclusions Interdisciplinary integrated management significantly improves the burden of IIH in terms of sick leave, presenteeism and healthcare consultations – particularly in socioeconomically underprivileged patient groups.

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“…Interessanterweise zeigt die Erweiterung der Opticusscheide auch bei gesunden Menschen ohne klinische Zeichen einer IIH eine positive Assoziation zum BMI, was bei der Interpretation dieser Befunde bedacht werden muss. MRT-Befunde wie sinus transversus Stenosen (3 %) und „empty sella“ (3,3 %) treten bei Gesunden hingegen selten auf und könnten somit für den diagnostischen Workflow weiter relevant sein 6 . Zusammenfassend lässt sich sagen, dass Faktoren wie Alter, BMI, Liquoröffnungsdruck und bildgebende Befunde diagnostisch hilfreich sein können, sich aber nicht zur Prognoseabschätzung eignen.…”

Section: Die Mrt-charakteristika Der Idiopathischen Intrakraniellen H...unclassified

Kopfschmerz News der DMKG

2023

Nervenheilkunde

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Updates on Recent Developments in Idiopathic Intracranial Hypertension

Cited by 10 publications

References 89 publications

Understanding the link between obesity and headache- with focus on migraine and idiopathic intracranial hypertension

Understanding the link between obesity and headache- with focus on migraine and idiopathic intracranial hypertension

An interdisciplinary integrated specialized one-stop outpatient clinic for idiopathic intracranial hypertension – an assessment of sick leave, presenteeism, and health care utilization

Kopfschmerz News der DMKG

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