Updates on germline predisposition in pediatric hematologic malignancies: What is the role of flow cytometry?
Nadine Demko,
Julia T. Geyer
Abstract:Hematologic neoplasms with germline predisposition have been increasingly recognized as a distinct category of tumors over the last few years. As such, this category was added to the World Health Organization (WHO) 4th edition as well as maintained in the WHO 5th edition and International Consensus Classification (ICC) 2022 classification systems. In practice, these tumors require a high index of suspicion and confirmation by molecular testing. Flow cytometry is a cost‐effective diagnostic tool that is routine… Show more
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