“…Proteomics provides new insights into the protein composition and expression at the subcellular level. In the last decade, several proteomic studies have been conducted using spermatozoa and seminal plasma (Amaral et al, ; Panner Selvam, & Agarwal, ; Panner Selvam, Agarwal, Sharma, & Samanta, ; Samanta et al, ) to understand the molecular pathways associated with male infertility and identification of potential protein biomarkers. High‐throughput instruments such as MALDI‐TOF and LC‐MS/MS systems are widely used to identify the proteomic profile of spermatozoa (Agarwal, Durairajanayagam, Halabi, Peng, & Vazquez‐Levin, ; Kosteria, Anagnostopoulos, Kanaka‐Gantenbein, Chrousos, & Tsangaris, ; du Plessis, Kashou, Benjamin, Yadav, & Agarwal, ).…”