Update on Seminal Vesiculitis in Stallions

Scheeren, V.F.C.; Sancler-Silva, Y. F. R.; Ali, Hesham A.; Kastelic, John P.; Alvarenga, Marco Antônio; Papa, Federico

doi:10.1016/j.jevs.2020.103234

Cited by 4 publications

(3 citation statements)

References 36 publications

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“…In humans, leukocytes also appear in ejaculates of fertile men (World Health Organization, 2021), and potential sources of leukocytes in ejaculate include the rete testis, the epididymis and the prostate (Wolff, 1995). In clinically evident cases, the presence of PMNs in equine ejaculates has been associated with epididymitis (Brinsko et al, 1992), seminal vesiculitis (Scheeren et al, 2020) and inflammation of other sites within the urogenital tract (Blanchard et al, 1988). We observed rapid loss of leukocyte cells after mixing with semen samples, suggesting that lymphoid cells could be very sensitive towards oxidative damage.…”

Section: Discussionmentioning

confidence: 99%

Flow cytometric detection and identification of different leukocyte subpopulations in stallion semen

Köhne,

Kirch,

Tönissen

et al. 2023

Reprod Domestic Animals

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To improve accuracy in evaluating stallion ejaculates, an antibody‐based, flow cytometric assay for the detection and identification of leukocyte subpopulations (CD4‐, CD8‐, CD21‐, CD172a‐positive cells) in stallion semen (n = 12) was established. For establishment of the assay, native semen was supplemented with blood leukocytes (control: 20% leukocytes, 80% sperm cells) and analysed by flow cytometry. Adding antioxidants (ascorbic acid and butylated hydroxytoluol) to semen immediately after collection inhibited rapid death of lymphoid cells in sperm leukocyte mixtures. In control set‐ups, 27.85 ± 5.7% of events were positive for CD4, CD8, CD21 or CD172a, while in native semen samples, leukocytes were scarce (0.114 ± 0.134%). The most abundant leukocyte subpopulation in semen was of lymphoid origin (CD4‐positive cells [0.015 ± 0.02%]), whereas CD21‐positive cells (B cells; 0.001 ± 0.001%) were virtually absent in ejaculates of fertile stallions. This presented flow cytometric assay for the detection and identification of different leukocyte population in equine antioxidant‐treated ejaculates can be used as an additional tool for spermatological examination in stallions.

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Section: Discussionmentioning

confidence: 99%

Flow cytometric detection and identification of different leukocyte subpopulations in stallion semen

Köhne,

Kirch,

Tönissen

et al. 2023

Reprod Domestic Animals

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“…When artificial insemination is used, penicillin G, streptomycin, amikacin or gentamicin are routinely used in semen extenders [ 133 ]. In clinical cases of orchitis or epididymitis, treatment includes the use of systemic antibiotics, based on semen culture and in vitro susceptibility testing of isolated bacteria [ 134 ]. In the rare cases of seminal vesiculitis, treatment with systemic antibiotics is considered to be difficult due to the impaired diffusion across mucosal cell borders into the seminal plasma [ 107 ]; there is a report in the international literature describing transurethral administration of antibiotics to the seminal vesicle [ 70 ].…”

Section: Therapeuticsmentioning

confidence: 99%

Clinical Aspects of Bacterial Distribution and Antibiotic Resistance in the Reproductive System of Equids

Tyrnenopoulou

Fthenakis

2023

Antibiotics

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Antibiotic administration is a standard therapeutic practice for the treatment of reproductive disorders of equids. This might lead to undesirable microbial imbalance and could favour the acquisition of antibiotic resistance. Therefore, it is imperative for clinicians to understand patterns of antibiotic resistance when considering and developing treatment regimes. Continued engagement of clinicians with novel alternative approaches to treat reproductive infections would be essential in order to address this rising threat within the One Health perspective. The objectives of the present review were to present the bacterial infections in the reproductive system of equids (horses, donkeys), to upraise the literature related to the issue of antibiotic resistance of bacteria causing these infections and to discuss the topic from a clinical perspective. Initially, the review summarised the various infections of the reproductive system of equids (genital system of females, genital system of males, mammary glands) and the causal bacteria, providing relevant information about horses and donkeys. Subsequently, the clinical therapeutics of these infections were presented, taking into account the significance of antibiotic resistance of bacteria as a limiting factor in treating the infections. Finally, approaches to circumvent antibiotic resistance in clinical settings were summarized. It was concluded that awareness regarding antibiotic resistance in equine reproductive medicine would increase, as we would recognise the multifaceted problem of resistance. Actions and initiatives within the One Health approach, minimizing the potential dissemination of resistant strains to humans and to the environment, with specific applications in medicine of equids should be appropriately instituted internationally.

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“…eminal vesiculitis (SV) and ejaculatory duct obstruction (EDO) are common clinical urogenital diseases (1). The etiology of SV is very complex (2).…”

mentioning

confidence: 99%

Application of seminal vesiculoscopy on the treatment of seminal vesiculitis

et al. 2023

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Objective: The development of seminal vesicle technology has greatly improved the efficiency of diagnosis and treatment of seminal vesiculitis, but its long-term efficacy and postoperative complications still need to be evaluated further. Patients and methods: Ninety-eight patients with seminal vesiculitis were randomly assigned to a traditional medical treatment control group (n = 49) and a seminal vesiculoscopy group (n = 49). The clinical efficacy of the two groups of patients, including blood sperm and pain, was evaluated 1 month after surgery. The maximum urine flow rate (MFR) and the average urine flow rate (AFR) were measured. Results: Compared with traditional medicine, seminal vesicle endoscopy has a higher clinical effect on seminal vesiculitis. Seminal vesicle therapy was more effective in reducing blood cells in patient’s semen and improving the patient’s urinary function. The seminal vesicle volume and seminal fructose were significantly improved. Conclusions: The efficacy of seminal vesiculoscopy for seminal vesiculitis is better than traditional medicine.

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Update on Seminal Vesiculitis in Stallions

Cited by 4 publications

References 36 publications

Flow cytometric detection and identification of different leukocyte subpopulations in stallion semen

Flow cytometric detection and identification of different leukocyte subpopulations in stallion semen

Clinical Aspects of Bacterial Distribution and Antibiotic Resistance in the Reproductive System of Equids

Application of seminal vesiculoscopy on the treatment of seminal vesiculitis

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