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“…Specific COX-2 inhibitors are effective against dysmenorrhea, but there are questions about its cardiovascular effects, which may restrict its use. We have already done a study to observe the possible differences in the therapy with selective COX-2 inhibitors (coxibes) in relation to the non-selective inhibitors (naproxen, ibuprofen), and no significant differences were observed between them [9,10].…”
Section: Introductionmentioning
confidence: 99%
“…Specific COX-2 inhibitors are effective against dysmenorrhea, but there are questions about its cardiovascular effects, which may restrict its use. We have already done a study to observe the possible differences in the therapy with selective COX-2 inhibitors (coxibes) in relation to the non-selective inhibitors (naproxen, ibuprofen), and no significant differences were observed between them [9,10].…”
Section: Introductionmentioning
confidence: 99%