Update on PET methods for D2 dopamine receptors in schizophrenia and bipolar disorder

Wong, Dean F.; Pearlson, G.D.; Tune, L.E.; Young, L. Trevor; Ross, Christopher A.; Villemagne, Victor L.; Dannals, Robert F.; Young, Deidra J.; Parker, Robert M.; Wilson, Alan A.; Ravert, Hayden T.; Links, Jonathan M.; Midha, K. K.; Wagner, Henry N.; Gjedde, Albert

doi:10.1016/0920-9964(89)90151-5

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“…Farde et al, (1987) found no increase in D 2 receptor number in the putamen or caudate nucleus. Wong et al (1989), who had found an increase in their initial study of schizophrenic patients, subsequently found a similar increase in patients with manic depressive psychosis, raising the possibility that an excess of D 2 receptors can be feature of psychotic illness in general.…”

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confidence: 98%