Update on Non-Interchangeability of Botulinum Neurotoxin Products
Mitchell F. Brin,
Mariana Nelson,
Nazanin Ashourian
et al.
Abstract:The growing use of botulinum neurotoxins (BoNTs) for medical and aesthetic purposes has led to the development and marketing of an increasing number of BoNT products. Given that BoNTs are biological medications, their characteristics are heavily influenced by their manufacturing methods, leading to unique products with distinct clinical characteristics. The manufacturing and formulation processes for each BoNT are proprietary, including the potency determination of reference standards and other features of the… Show more
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