Update on management of Barrett's esophagus

Macias-García, Fernando; Domínguez–Muñoz, J. Enrique

doi:10.4292/wjgpt.v7.i2.227

Cited by 5 publications

(4 citation statements)

References 78 publications

(63 reference statements)

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“…The present study shows that the overall five‐year survival rates of esophageal cancer have increased in the examined study period. We believe that this is not only due to the improvement in surgical techniques and adjuvant therapy, but also due to the early diagnosis of an increased number of esophageal cancer cases owing to the increasing use of upper gastrointestinal endoscopy . Interestingly, the five‐year survival rates for EAC were higher compared to ESCC, especially after 1992, which is consistent with the previous studies .…”

Section: Discussionsupporting

confidence: 88%

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Trends in the incidence and survival of patients with esophageal cancer: A SEER database analysis

et al. 2020

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Background: Recent studies have indicated that the incidence of esophageal cancer has declined in the past decade in the U.S. However, trends in the incidence and survival have not been thoroughly examined. Methods: Data from 46 063 patients with esophageal cancer between 1973 and 2015 were collected from the Surveillance, Epidemiology, and End Results database. The trends in the age-adjusted incidence and survival were analyzed using joinpoint regression models. Results: The age-adjusted incidence of esophageal cancer increased from 5.55 to 7.44 per 100 000 person-years between 1973 and 2004. Later, it decreased at an annual percentage change of 1.23%. In the last 40 years, the strong male predominance increased slightly. Importantly, the percentage of patients with localized stage of squamous cell cancer decreased. It was observed that the incidence of esophageal squamous cell carcinoma declined since 1986, while the incidence of esophageal adenocarcinoma sharply increased since 1973 and surpassed the rate of squamous cell cancer, mainly due to the increase in the incidence among men. Consistently, the estimated 40-year limited-duration prevalence of esophageal adenocarcinoma was higher than that of esophageal squamous cell carcinoma. Additionally, we observed a modest but significant improvement in survival during the study period. Conclusion: The incidence of esophageal squamous cell carcinoma has decreased significantly over the past four decades in the U.S., while the incidence of adenocarcinoma has increased, particularly among men. Overall, the longterm survival of patients with esophageal cancer is poor but it has improved over the past decades, especially for the localized disease. Key pointsSignificant findings of the study The incidence of esophageal cancer has decreased at an annual percentage change of 1.23% since 2004. The incidence of esophageal adenocarcinoma has sharply increased since 1973 and surpassed the rate of squamous cell cancer, mainly due to the increase in the incidence among men. What this study adds There has been a shift in the prevalence of esophageal cancer histological subtypes over the past decades in the U.S. We found that the incidence of esophageal squamous cell carcinoma has continued to decrease, while the esophageal adenocarcinoma rate has continued to increase.

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Section: Discussionsupporting

confidence: 88%

“…This increasing prevalence of BE is likely to result in the increasing rates of EAC in the next few decades. Consequently, the strategy for the prevention and control of EAC relies on upper endoscopy coupled with biopsy to identify BE in patients with GERD and regular endoscopic surveillance in BE patients …”

Section: Discussionmentioning

confidence: 99%

Trends in the incidence and survival of patients with esophageal cancer: A SEER database analysis

et al. 2020

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“…Although recent analysis of SEER data showed that 5-year survival rates for all age patients with esophageal cancer increased from 1973 to 2010 (for both localized and regional stages), information on survival among older patients remains sparse [ 51 ]. It has been speculated that survival of patients with esophageal cancer was slowly improving due to better surgical techniques, adjuvant therapy, and increasing use of upper gastrointestinal endoscopy for early diagnosis [ 51 , 52 ]. However, it seems that this may not be the case for older patients for whom a deceleration in survival could be associated with changing patterns of histotype-specific incidence with esophageal adenocarcinoma rates surpassing the rates of squamous cell carcinoma [ 51 , 53 ].…”

Section: Discussionmentioning

confidence: 99%

Underlying mechanisms of change in cancer prevalence in older U.S. adults: contributions of incidence, survival, and ascertainment at early stages

Akushevich

Yashkin

Kovtun

et al. 2022

Cancer Causes Control

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Purpose To quantitatively evaluate contributions of trends in incidence, relative survival, and stage at diagnosis to the dynamics in the prevalence of major cancers (lung, prostate, colon, breast, urinary bladder, ovaries, stomach, pancreas, esophagus, kidney, liver, and skin melanoma) among older U.S. adults age 65 +. Methods Trend partitioning was applied to the Surveillance, Epidemiology, and End Results Program data for 1973–2016. Results Growth of cancer prevalence in older adults decelerated or even decreased over time for all studied cancers due to decreasing incidence and improving survival for most of cancers, with a smaller contribution of the stage at cancer diagnosis. Changes in the prevalence of cancers of the lung, colon, stomach, and breast were predominantly due to decreasing incidence, increasing survival and more frequent diagnoses at earlier stages. Changes in prevalence of some other cancers demonstrated adverse trends such as decreasing survival in localized and regional stages (urinary bladder and ovarian) and growing impact of late-stage diagnoses (esophageal cancer). Conclusion While decelerating or decreasing prevalence of many cancers were due to a beneficial combination of decreasing incidence and increasing survival, there are cancers for which decelerating prevalence is due to lack of improvement in their stage-specific survival and/or increasing frequency of diagnosis at advanced stages. Overall, if the observed trends persist, it is likely that the burden associated with cancer prevalence in older U.S. adults will be lower comparing to projections based on constant increasing prevalence have previously estimated.

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“…There is no statistical significance between the groups. It is important remember: clinical or surgical treatment does not suspend the obligatory surveillance for the transformation of BE into adenocarcinoma with endoscopy [ [13], [14]]. This surveillance is valid only for patients diagnosed with BE, patients with GERD have no indication of endoscopic surveillance unless there are other warning signs or risk factors for Barrett's esophagus [ [15], 16].…”

Section: Discussionmentioning

confidence: 99%

Regression of Barrett’s Esophagus: Is There a Difference between Clinical and Surgical Treatment?

Lima¹,

Pinheiro²,

Pinto³

et al. 2017

JPP

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Abstract:Objective: To evaluate the response to clinical and surgical treatment of Walter Cantídio University Hospital patients who were diagnosed with Barrett's esophagus between 2012 and 2016. Methodology: From the database analysis of Walter Cantídio University Hospital's pathology service, we identified all patients with a diagnosis of Barrett's esophagus between 2012 and 2016. We analyzed the patients' medical records and collected epidemiological and clinical data. Results: 22 patients were included in the study, 13 of whom were surgically treated and 9 were clinically treated. The regression was 33.3% in the clinical group and 30.7% in the surgical group, with no statistical difference between these two groups. Conclusions: The results show synchrony with data from the medical literature regarding the response of Barrett's esophagus to clinical and surgical treatment.

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Update on management of Barrett's esophagus

Cited by 5 publications

References 78 publications

Trends in the incidence and survival of patients with esophageal cancer: A SEER database analysis

Trends in the incidence and survival of patients with esophageal cancer: A SEER database analysis

Underlying mechanisms of change in cancer prevalence in older U.S. adults: contributions of incidence, survival, and ascertainment at early stages

Regression of Barrett’s Esophagus: Is There a Difference between Clinical and Surgical Treatment?

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