Update on lung transplantation in children

Gaynor, J. William; Nd, Bridges; Bj, Clark; Tl, Spray

doi:10.1097/00008480-199806000-00006

Cited by 12 publications

(2 citation statements)

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“…[50][51][52] Cystic fibrosis accounts for the majority of lung transplants, with primary pulmonary hypertension as an indication for transplantation in 14-17% of patients. For certain patients, including those with congenital heart disease, heart-lung transplantation may be necessary.…”

Section: Transplantationmentioning

confidence: 99%

Severe paediatric pulmonary hypertension: new management strategies

Rashid

2005

Archives of Disease in Childhood

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Section: Transplantationmentioning

confidence: 99%

Severe paediatric pulmonary hypertension: new management strategies

Rashid

2005

Archives of Disease in Childhood

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“…Heartlung transplantation in children was performed in a few centres in the USA and the UK in the 1980s [1,2], but it was not until the 1990s that surgeons in selected centres in North America and Europe began to perform isolated lung transplantation in children. Subsequently, there have been a few reports documenting early success in adopting the surgical techniques, immunosuppression and post-transplant care to infants and children with reasonable outcomes [3][4][5][6][7].…”

mentioning

confidence: 99%

Paediatric lung transplantation

Mallory

Spray²

2004

Eur Respir J

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Since 1990, lung transplantation has been performed in infants, children and adolescents in small numbers, and the numbers, in comparison with adult transplants, remain small today. The indications for lung transplantation are similar in childhood when compared with adults, but the disease entities are distinct.In children, severe pulmonary vascular disease is most commonly associated with developmental abnormalities or congenital heart disease, as opposed to idiopathic pulmonary hypertension. Cystic fibrosis is the dominant indication for lung transplantation in older childhood and adolescence.The operative approach to lung transplantation in early life differs from that in adults, in that cardiopulmonary bypass is more likely to be utilised and bilateral lung transplantation is strongly preferred to single lung transplantation. Living donor lung transplantation is proportionately more common in children and adolescents than in adults. Post-transplant complications related to viral infection and post-transplant lymphoproliferative disease are more common and more likely to be severe and lifethreatening. Bronchiolitis obliterans is the most important complication after paediatric lung transplantation and limits both the quality of life and duration of survival, as in adults.

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Pediatric Pulmonary Hypertension

Tissot

Beghetti

2012

Pediatric Cardiovascular Medicine

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Update on lung transplantation in children

Cited by 12 publications

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Severe paediatric pulmonary hypertension: new management strategies

Severe paediatric pulmonary hypertension: new management strategies

Paediatric lung transplantation

Pediatric Pulmonary Hypertension

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