“…IAB has been proposed as a marker of the structurally altered and electromechanically dysfunctional LA, and, at the same time, as an electrophysiological risk factor and substrate for AF and conditions related to AF, such as congestive heart failure [15,16]. It is important to mention that interatrial dyssynchrony caused by IAB, beyond generating atrial remodeling (increased atrial pressure, atrial dilation and atrial fibrosis), produces endothelial dysfunction, contributing via both factors to enhanced local thrombogenesis, responsible for cardioembolic events [17].…”