Update in management of head and neck sarcoma

Hoffman, Henry T.; Robinson, Robert A.; Spiess, Jeffrey L.; Buatti, John M.

doi:10.1097/01.cco.0000127880.69877.75

Cited by 38 publications

(30 citation statements)

References 53 publications

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“…Head and neck sarcoma treatment is based on tumor type, stage, location, size and also patient age. Chemotherapy and radiotherapy are the usual combined treatment used 7,[12][13][14] . Compared to other locations, head and neck sarcomas have a worse prognosis, since the entire tumor removal is impaired by its proximity to vital structures 4,15,16 , which increases the risk of recurrences and functional and cosmetic deformities 5 .…”

Section: Introductionmentioning

confidence: 99%

Clinicopathological study of patients with head and neck sarcomas

Pacheco¹,

Alves²,

Mota³

et al. 2011

Braz. j. otorhinolaryngol. (Impr.)

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Sarcomas are rare tumors, mainly stemming from the embryonic mesoderm, with a high grade of morbidity and mortality.Objective: To carry out a retrospective study of head and neck sarcoma cases between 1999 and 2008 in three specialized centers in the city of Fortaleza. Materials and Methods:Data collection was based on the charts of the patients in the study. For statistical analysis purposes we used the chi-square associations and the z test for proportions.Results: We found records of 36 patients, and the most affected ones were adult brown males, in the age range between 20 and 59 years -mean age of 39.7. The man/woman ratio was 1.76:1. The most prevalent histological type was the rhabdomyosarcoma and their most common locations were the face and the neck. Most of the sample was made up of live patients without evidence of the disease in the last visit -41.6% of the cases. The most common treatment modes were the combination of surgery + radiotherapy + chemotherapy and surgery + radiotherapy, with 27.8% of the cases each. Conclusion:Sarcomas have a great histological variability and may have numerous locations. Since these are rare and not well-known lesions, new epidemiological studies must be carried out in order to enhance our understanding of the disease. Braz J Otorhinolaryngol. 2011;77(3):385-90. ORIGINAL ARTICLE

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Section: Introductionmentioning

confidence: 99%

Clinicopathological study of patients with head and neck sarcomas

Pacheco¹,

Alves²,

Mota³

et al. 2011

Braz. j. otorhinolaryngol. (Impr.)

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“…The incidence of sarcoma of Sino nasal tract is only 30% [1]. This is said to be still more uncommon because of the transformation of schwannoma to a soft tissue sarcoma.…”

Section: Discussionmentioning

confidence: 99%

“…They constitute about 4-5% of all childhood malignancies [1]. Adult rhabdomyosarcomas are relatively very rare.…”

Section: Introductionmentioning

confidence: 99%

A Case of Rhabdomyosarcoma of the Sino Nasal Tract in an Adult Male: A Rare Case Report with Review of Literature

Manickam¹,

Singh²,

Sengupta³

et al. 2015

Surgery Curr Res

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“…However, these tumors invade areas of difficult surgical access, making it difficult to achieve adequate surgical margins in head and neck area where there are no compartments as in the extremities, resulting in a high risk of local recurrence [4,5]. In head and neck the most common site of involvement is the scalp, followed by the sinonasal tract and the most common histological types are unclassifiable sarcoma, angiosarcoma and Malignant fibrous histiocytoma (MFH) [6].…”

Section: Introductionmentioning

confidence: 99%

Maxillary Sinus Sarcomas: Epidemiological and Clinicopathological Experience of 25 Years in a National Reference Cancer Center

Salcedo-Hernández

Lino-Silva

Luna-Ortiz

2012

Indian J Otolaryngol Head Neck Surg

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The aim of this study was to report our experience with malignant soft tissue tumors of the maxillary sinus in the period between 1985 to 2010. This is a retrospective case study in a tertiary cancer center setting. Review of patient's records and new evaluation of pathological specimens were made for 20 patients (14 men and 6 women) still met present criteria. After review the most common histological diagnoses were malignant peripheral nerve sheath tumor and malignant fibrous histiocytoma. There are male sex predilection, the median age was 38.9 years; 95% of tumors were [5 cm, 80% were high grade, 0% have metastatic disease at the diagnosis and the tumors were initially treated by surgical resection had better survival (p = 0.02). We present the results of a one of the larger series published to date in maxillary sinus sarcomas where analyzed the clinicopathological characteristics of 20 cases.

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Update in management of head and neck sarcoma

Abstract: Progress in improving the treatment of sarcoma of the head and neck has been slow due to the lack of a large clinical experience with this rare neoplasm. Advances continue and are anticipated to be most striking in the study of genetic mechanisms.

Cited by 38 publications

References 53 publications

Clinicopathological study of patients with head and neck sarcomas

Clinicopathological study of patients with head and neck sarcomas

A Case of Rhabdomyosarcoma of the Sino Nasal Tract in an Adult Male: A Rare Case Report with Review of Literature

Maxillary Sinus Sarcomas: Epidemiological and Clinicopathological Experience of 25 Years in a National Reference Cancer Center

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