Update and review of contrast-associated acute kidney injury

Impact of iodine contrast media on gamma camera-based GFR and factors affecting the difference between serum creatinine-based estimated GFR and Gate’s GFR

“…Acute kidney injury (AKI) due to ICM occurred in approximately 6.4% of patients in a meta-analysis [36]; however, there may be milder and temporary kidney injuries that do not meet these criteria. After the intravascular injection of ICM, rapid renal vasodilation followed by long vasoconstriction, which is the main cause of renal ischemia and tubular toxicity, occurs [34,37]. In this study, none of the patients with decreased gGFR after the ICM administration required treatment for CIN and they did not show significant decline in eGFR at subsequent examination; moreover, the temporary reduction of renal function may recover rapidly.…”

“…In this study, none of the patients with decreased gGFR after the ICM administration required treatment for CIN and they did not show significant decline in eGFR at subsequent examination; moreover, the temporary reduction of renal function may recover rapidly. In most AKI cases, an eGFR reduction occurs; however, persistent kidney failure requiring dialysis or transplantation is rare [37]. A temporal reduction in renal function occurred in cases that showed a large reduction in gGFR and gGFR/eGFR ratio compared to the previous examination without ICM administration before 99m Tc-DTPA scintigraphy.…”