Abstract:Roundabout (Robo) receptors have many important roles including mediating the migration of the growth cone and neurons, promoting axonal growth and development of nerve fascicles, and guiding the growth direction of central nervous system by binding Slit. To better understand the role of Robo in peripheral nervous system, this study investigated the expression profile of Robo1 in the dorsal root ganglia (DRG) of adult rats following sciatic nerve transection (SNT). Adult Sprague-Dawley rats that were untreated… Show more
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