UP-2.026: Antibiotic Prophylaxis During Extracorporeal Shock Wave Lithotripsy (ESWL) in the Prevention of Urinary Tract Infection in Patients with Sterile Urine Before the Procedure

CUA Guidelines on antibiotic prophylaxis for urologic procedures

“…Eight met the eligibility criteria for final inclusion in the systematic review. [8][9][10][11][12][13][14][15] Eight controlled trials randomized a total of 940 study participants ( Table 1). The incidence of UTI and fever were 4.2% and 3.4%, respectively.…”

Antibiotic Prophylaxis for Shock Wave Lithotripsy in Patients with Sterile Urine Before Treatment May be Unnecessary: A Systematic Review and Meta-Analysis

“…Hematuria was another common symptom after SWL and Ghazimoghaddam et al reported no statistically significant difference in the incidence of hematuria between the 2 groups (p Ͼ0.05). 16 Furthermore, overall complaints did not differ significantly between the groups (p Ͼ0.05). 13…”

“…After referring to full texts, 9 publications (RCTs) involving 1,364 patients were included in the study. [13][14][15][16][17][18][19][20][21] Characteristics and quality of the included studies are presented in tables 1 and 2, and the search flow diagram is presented in figure 1. There were no significant differences in baseline information between the 2 groups.…”

“…14,16 -18,20,21 There were 6 studies that compared a single type of antibiotic with placebo or no treatment and 3 that compared 2 different antibiotics with control. 13,16,19 Of the studies 4 used penicillins, 14,17,19,20 3 used quinolone, 13,15,18 2 used a SMZϩTMP combination, 16,20 and 1 used cephalosporins, 13 nitrofurantoin, 16 aminoglycosides 19 or ␤-lactam, 21 respectively. Our review of funnel plots excluded publication bias.…”

“…[13][14][15][16][17][18]20 In these RCTs UTI developed in 0% to 14.0% of patients after SWL, including 0% to 14.0% of controls and 0% to 12.0% of those on prophylaxis (table 4). Furthermore, there were no significant differences between the 2 groups in the incidence of short-term UTI (RR 0.55, 95% CI 0.29 -1.04, p ϭ 0.06), the incidence of midterm UTI (RR 0.49, 95% CI 0.05-5.34, p ϭ 0.56) 13,18 and the overall incidence of UTI (RR 0.54, 95% CI 0.29 -1.01, p ϭ 0.05, fig.…”