Unveiling the therapeutic potential of airpotato yam rhizome against colorectal cancer: a network pharmacology approach
Yiwen Xie,
Sumei Xu,
Zhiyun Chen
et al.
Abstract:ObjectiveThe objective of this investigation was to elucidate the key active compounds and molecular mechanisms underlying the therapeutic potential of airpotato yam rhizome (AYR) in colorectal cancer (CRC) treatment.MethodsBy utilizing network pharmacology and molecular docking, key targets and signaling pathways of AYR against CRC were predicted and subsequently validated in cellular and mouse xenograft models.ResultsThis study initially predicted that quercetin was the primary compound in AYR that might hav… Show more
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