Unveiling the potential of selenium-enriched tea: Compositional profiles, physiological activities, and health benefits

Selenium-Mediated (−)-Epigallocatechin-3-Gallate Dynamics via Flavanone-3-Hydroxylase Regulation of Flavonoid Biosynthesis in Fu Tea (Camellia sinensis (L.) O. Kuntze)

“…The application of nano-Se to tea in the summer reduces caffeine and decreases the bitter flavor of tea. 7,51 Meanwhile, selenium increased the accumulation of myricetin 3-galactoside and schaftoside in tea. Myricetin 3-galactoside is produced by galactosylation of myricetin catalyzed by rCsUGT78A15.…”

“…Differential metabolites in tea were mainly associated with theanine synthase, glutathione reductase, glutathione peroxidases (GPxs), S-adenosylmethionine synthase, and shikimate dehydrogenase. 7,32 Glutathione is a central component of metal scavenging and has an instrumental role in protecting plants from oxidative stress caused by metal exposure due to the high affinity of metals for its thiol (-SH) moiety and is a precursor of phytochelatins (PCs). 33 The cysteine residues on glutathione make it an important antioxidant, and selenium doping is challenging, with glutathione peroxidase reducing oxidized glutathione peroxidase via thiol-containing compounds like the reducing cofactor glutathione.…”

“…Calculated on the basis of a daily intake of below 15 g of selenium-enriched tea, the selenium intake is less than 30 μg, which is not above the upper safety limit for selenium, and selenium-enriched tea can be used as a moderate and safe source of dietary selenium supplementation. 7,8 The toxicity and bioavailability of selenium are intimately associated with the content of selenium and the morphology of selenium in selenium-fortified foods. 2 Foliar selenium spraying dramatically increased the selenium content of wheat (Triticum aestivum L.) kernels, where the main organic selenium species was selenomethionine, occupying 69.9−86.6% of the overall selenium, with a secondary contribution of selenocysteine (7.9−14.5%).…”

“…11,12 Tea absorbs exogenous selenium converting it to organic selenium (selenopolysaccharides, selenopolyphenols, selenoproteins, seleno-substituted amino acids, etc.). 7 Selenium-enriched tea has antioxidant, anti-inflammatory, and gut-protective benefits. Selenium-enriched ingredients have been demonstrated to function as a strategy to alleviate Alzheimer's disease by modulating the vicious cycle of autophagy, ROS overload, and inflammation.…”

“…Reducing the particle size of selenium-enriched tea can improve its antioxidant activity, and it can be used to make miniature tea powder and related food products to improve the utilization of selenium-enriched tea. 7,16 Selenium-enriched tea can also participate in the synthesis of selenium nanoparticles, which can increase the intake of the active ingredients in selenium-enriched tea and reduce the risk of excessive selenium intake. 17 Fu tea is a popular beverage among ethnic minorities in China's border regions, whose main diet consists of meat and cheese and which possesses excellent antioxidant and antigreasy properties.…”