Unveiling the metabolic landscape of pulmonary hypertension: insights from metabolomics
Huixue Ba,
Yingfan Guo,
Yujie Jiang
et al.
Abstract:Pulmonary hypertension (PH) is regarded as cardiovascular disease with an extremely poor prognosis, primarily due to irreversible vascular remodeling. Despite decades of research progress, the absence of definitive curative therapies remains a critical challenge, leading to high mortality rates. Recent studies have shown that serious metabolic disorders generally exist in PH animal models and patients of PH, which may be the cause or results of the disease. It is imperative for future research to identify crit… Show more
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