Unveiling the antimicrobial potency and binding interaction between sulfonamide substituted Schiff’s bases and BSA protein: An integrated experimental and theoretical approach

Synthesis, quantum chemical calculations, in silico and in vitro bioactivity of a sulfonamide-Schiff base derivative

“…The primary cause of morbidity and mortality worldwide is the growing resistance of microorganisms to currently available antimicrobial medications [ 17 , 18 ]. Some adverse effects and drug resistance emphasize the importance of discovering new potential drug candidates [ 17 , 19 ]. In computer-aided drug design systems, physicochemical, molecular docking, and ADMET predictions are important criteria for evaluating newly designed compounds.…”