Unveiling novel double-negative prostate cancer subtypes through single-cell RNA sequencing analysis
Siyuan Cheng,
Lin Li,
Yunshin Yeh
et al.
Abstract:Recent advancements in single-cell RNA sequencing (scRNAseq) have facilitated the discovery of previously unrecognized subtypes within prostate cancer (PCa), offering new insights into cancer heterogeneity and progression. In this study, we integrated scRNAseq data from multiple studies, comprising publicly available cohorts and data generated by our research team, and established the Human Prostate Single cell Atlas (HuPSA) and Mouse Prostate Single cell Atlas (MoPSA) datasets. Through comprehensive analysis,… Show more
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