Unveiling contrasts in microbiota response: A1c control improves dysbiosis in low-A1c T2DM, but fails in high-A1c cases—a key to metabolic memory?
Thiago Fraga Napoli,
Ramon V Cortez,
Luiz Gustavo Sparvoli
et al.
Abstract:IntroductionType 2 diabetes mellitus (T2DM) is associated with dysbiosis in the gut microbiota (MB). Individually, each medication appears to partially correct this. However, there are no studies on the response of the MB to changes in A1c. Therefore, we investigated the MB’s response to intensive glycemic control.Research design and methodsWe studied two groups of patients with uncontrolled T2DM, one group with an A1c <9% (18 patients—G1) and another group with an A1c >9% (13 patients—G2), aiming for at… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.